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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">microbe</journal-id><journal-title-group><journal-title xml:lang="ru">Проблемы особо опасных инфекций</journal-title><trans-title-group xml:lang="en"><trans-title>Problems of Particularly Dangerous Infections</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0370-1069</issn><issn pub-type="epub">2658-719X</issn><publisher><publisher-name>Russian Research Anti-Plague Institute “Microbe”</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21055/0370-1069-2008-1(95)-52-55</article-id><article-id custom-type="elpub" pub-id-type="custom">microbe-1074</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>БИОТЕХНОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>BIOTECHNOLOGY</subject></subj-group></article-categories><title-group><article-title>Изучение биокинетических особенностей и оптимизация условий культивирования штаммов холерного вибриона – продуцентов протективных антигенов, перспективных для внедрения в производство</article-title><trans-title-group xml:lang="en"><trans-title>A Study of Biokinetic Peculiarities and Optimization of the Conditions for Culturing Vibrio cholerae Strains Overproducing Protective Antigens Suitable for Use in the Production</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Волох</surname><given-names>О. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Volokh</surname><given-names>O. A.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шепелёв</surname><given-names>И. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Shepelev</surname><given-names>I. A.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Заднова</surname><given-names>С. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Zadnova</surname><given-names>S. P.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Крепостнова</surname><given-names>И. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Krepostnova</surname><given-names>I. M.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Еремин</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Yeremin</surname><given-names>S. A.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Российский научно-исследовательский противочумный институт «Микроб», Саратов</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian Anti-Plague Research Institute “Microbe”, Saratov</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2008</year></pub-date><pub-date pub-type="epub"><day>20</day><month>02</month><year>2008</year></pub-date><volume>0</volume><issue>1(95)</issue><fpage>52</fpage><lpage>55</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Волох О.А., Шепелёв И.А., Заднова С.П., Крепостнова И.М., Еремин С.А., 2008</copyright-statement><copyright-year>2008</copyright-year><copyright-holder xml:lang="ru">Волох О.А., Шепелёв И.А., Заднова С.П., Крепостнова И.М., Еремин С.А.</copyright-holder><copyright-holder xml:lang="en">Volokh O.A., Shepelev I.A., Zadnova S.P., Krepostnova I.M., Yeremin S.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.microbe.ru/jour/article/view/1074">https://journal.microbe.ru/jour/article/view/1074</self-uri><abstract/><trans-abstract xml:lang="en"/><kwd-group xml:lang="ru"><kwd>Vibrio cholerae</kwd><kwd>глубинное культивирование</kwd><kwd>протективные антигены</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Vibrio cholerae</kwd><kwd>submerged cultivation</kwd><kwd>protective antigens</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">грант РФФИ ОФИ № 06­-04-08122</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Громова О.В., Джапаридзе М.Н., Дятлов И.А. и др. 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