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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">microbe</journal-id><journal-title-group><journal-title xml:lang="ru">Проблемы особо опасных инфекций</journal-title><trans-title-group xml:lang="en"><trans-title>Problems of Particularly Dangerous Infections</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0370-1069</issn><issn pub-type="epub">2658-719X</issn><publisher><publisher-name>Russian Research Anti-Plague Institute “Microbe”</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21055/0370-1069-2019-1-17-25</article-id><article-id custom-type="elpub" pub-id-type="custom">microbe-1121</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group></article-categories><title-group><article-title>Особенности эпидемической ситуации по лихорадке Западного Нила на территории Российской Федерации в 2018 г. и прогноз ее развития на 2019 г.</article-title><trans-title-group xml:lang="en"><trans-title>Peculiarities of the Epidemic Situation on West Nile Fever in the Territory of the Russian Federation in 2018 and Forecast of its Development in 2019</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Алексейчик</surname><given-names>И. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Alekseychik</surname><given-names>I. O.</given-names></name></name-alternatives><bio xml:lang="ru"><p> Российская Федерация, 400131, Волгоград, ул. Голубинская, 7</p></bio><bio xml:lang="en"><p>7, Golubinskaya St., Volgograd, 400131, Russian Federation</p></bio><email xlink:type="simple">vari2@sprint-v.com.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Путинцева</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Putintseva</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Российская Федерация, 400131, Волгоград, ул. Голубинская, 7</p></bio><bio xml:lang="en"><p>7, Golubinskaya St., Volgograd, 400131, Russian Federation</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Смелянский</surname><given-names>В. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Smelyansky</surname><given-names>V. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Российская Федерация, 400131, Волгоград, ул. Голубинская, 7</p></bio><bio xml:lang="en"><p>7, Golubinskaya St., Volgograd, 400131, Russian Federation</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бородай</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Boroday</surname><given-names>N. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Российская Федерация, 400131, Волгоград, ул. Голубинская, 7</p></bio><bio xml:lang="en"><p>7, Golubinskaya St., Volgograd, 400131, Russian Federation</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Алиева</surname><given-names>А. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Alieva</surname><given-names>A. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Российская Федерация, 400131, Волгоград, ул. Голубинская, 7</p></bio><bio xml:lang="en"><p>7, Golubinskaya St., Volgograd, 400131, Russian Federation</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Агаркова</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Agarkova</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Российская Федерация, 400131, Волгоград, ул. Голубинская, 7</p></bio><bio xml:lang="en"><p>7, Golubinskaya St., Volgograd, 400131, Russian Federation</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чеснокова</surname><given-names>С. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Chesnokova</surname><given-names>S. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Российская Федерация, 400131, Волгоград, ул. Голубинская, 7</p></bio><bio xml:lang="en"><p>7, Golubinskaya St., Volgograd, 400131, Russian Federation</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Фомина</surname><given-names>В. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Fomina</surname><given-names>V. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Российская Федерация, 400131, Волгоград, ул. Голубинская, 7</p></bio><bio xml:lang="en"><p>7, Golubinskaya St., Volgograd, 400131, Russian Federation</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Батурин</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Baturin</surname><given-names>A. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Российская Федерация, 400131, Волгоград, ул. Голубинская, 7</p></bio><bio xml:lang="en"><p>7, Golubinskaya St., Volgograd, 400131, Russian Federation</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Жуков</surname><given-names>К. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Zhukov</surname><given-names>K. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Российская Федерация, 400131, Волгоград, ул. Голубинская, 7</p></bio><bio xml:lang="en"><p>7, Golubinskaya St., Volgograd, 400131, Russian Federation</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шахов</surname><given-names>Л. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Shakhov</surname><given-names>L. O.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Российская Федерация, 400131, Волгоград, ул. Голубинская, 7</p></bio><bio xml:lang="en"><p>7, Golubinskaya St., Volgograd, 400131, Russian Federation</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пакскина</surname><given-names>Н. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Pakskina</surname><given-names>N. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Российская Федерация, 127994, Москва, Вадковский переулок, дом 18, строение 5 и 7</p></bio><bio xml:lang="en"><p>18, Bld. 5 and 7, Vadkovsky Pereulok, Moscow, 127994, Russian Federation</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Демина</surname><given-names>Ю. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Demina</surname><given-names>Yu. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Российская Федерация, 127994, Москва, Вадковский переулок, дом 18, строение 5 и 7</p><p>Российская Федерация,125993, Москва, ул. Б аррикадная, 2/1</p></bio><bio xml:lang="en"><p>18, Bld. 5 and 7, Vadkovsky Pereulok, Moscow, 127994, Russian Federation</p><p>2/1, Barrikadnaya St., Moscow, 125993, Russian Federation</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ежлова</surname><given-names>Е. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Ezhlova</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Российская Федерация, 127994, Москва, Вадковский переулок, дом 18, строение 5 и 7</p></bio><bio xml:lang="en"><p>18, Bld. 5 and 7, Vadkovsky Pereulok, Moscow, 127994, Russian Federation</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Викторов</surname><given-names>Д. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Viktorov</surname><given-names>D. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Российская Федерация, 400131, Волгоград, ул. Голубинская, 7</p></bio><bio xml:lang="en"><p>7, Golubinskaya St., Volgograd, 400131, Russian Federation</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Топорков</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Toporkov</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Российская Федерация, 400131, Волгоград, ул. Голубинская, 7</p></bio><bio xml:lang="en"><p>7, Golubinskaya St., Volgograd, 400131, Russian Federation</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФКУЗ «Волгоградский научно-исследовательский противочумный институт»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Volgograd Research Anti-Plague Institute</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Федеральная служба по надзору в сфере защиты прав потребителей и благополучия человека</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal Service for Surveillance in the Sphere of Consumers Rights Protection and Human Welfare</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Федеральная служба по надзору в сфере защиты прав потребителей и благополучия человека&#13;
ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal Service for Surveillance in the Sphere of Consumers Rights Protection and Human Welfare&#13;
Russian Medical Academy of Continuing Professional Education</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>02</day><month>04</month><year>2019</year></pub-date><volume>0</volume><issue>1</issue><fpage>17</fpage><lpage>25</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Алексейчик И.О., Путинцева Е.В., Смелянский В.П., Бородай Н.В., Алиева А.К., Агаркова Е.А., Чеснокова С.Н., Фомина В.К., Батурин А.А., Жуков К.В., Шахов Л.О., Пакскина Н.Д., Демина Ю.В., Ежлова Е.Б., Викторов Д.В., Топорков А.В., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Алексейчик И.О., Путинцева Е.В., Смелянский В.П., Бородай Н.В., Алиева А.К., Агаркова Е.А., Чеснокова С.Н., Фомина В.К., Батурин А.А., Жуков К.В., Шахов Л.О., Пакскина Н.Д., Демина Ю.В., Ежлова Е.Б., Викторов Д.В., Топорков А.В.</copyright-holder><copyright-holder xml:lang="en">Alekseychik I.O., Putintseva E.V., Smelyansky V.P., Boroday N.V., Alieva A.K., Agarkova E.A., Chesnokova S.N., Fomina V.K., Baturin A.K., Zhukov K.V., Shakhov L.O., Pakskina N.D., Demina Y.V., Ezhlova E.V., Viktorov D.V., Toporkov A.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.microbe.ru/jour/article/view/1121">https://journal.microbe.ru/jour/article/view/1121</self-uri><abstract><p>Эпидемический подъем заболеваемости населения лихорадкой Западного Нила (ЛЗН ) в сезон 2018 г. наблюдался на территории стран-членов Европейского Союза и граничащих с ними государств и превысил значения всех ранее зафиксированных эпидемических подъемов 2010–2012 гг. Рост заболеваемости зарегистрирован в США и Канаде, однако он не превысил показателей эпидемических подъемов 2007–2012 гг. На территории Российской Федерации эпидемический процесс ЛЗН активизировался, в основном, на территории Южного и Северо-Кавказского федеральных округов. В целом по России показатели заболеваемости в 2018 г. в два раза ниже среднемноголетних, но заметно превысили 2017 г. Эпидемический процесс имел ряд особенностей в сезонности проявления, структуре заболеваемости и клиническом проявлении ЛЗН . Генотипирование выделенных фрагментов РНК ВЗН из клинического и биологического материала показало, что на европейской части России циркулировали 1-й, 2-й и 4-й генотипы вируса Западного Нила. Прогноз развития эпидемической ситуации в 2019 г. предполагает дальнейший рост заболеваемости и не исключает возможности значительного локального повышения заболеваемости ЛЗН в отдельных субъектах Российской Федерации.</p></abstract><trans-abstract xml:lang="en"><p>The epidemic rise in the incidence of West Nile fever (WNF) in the season of 2018 was observed in the countries of the European Union (EU) and bordering states and exceeded the values of all previously recorded epidemic rises of 2010–2012. An increase in the incidence rate was registered in the USA and Canada, however, it did not exceed the indicators of epidemic rises of 2007–2012. In the territory of the Russian Federation, the WNF epidemiological process became more intense mainly in the territory of the Southern and North Caucasian Federal Districts. In general, in Russia, the incidence rates were 2 times lower than the average annual rates, but significantly exceeded those of 2017. The epidemic process had a number of peculiarities in the seasonality, the structure of morbidity and the clinical manifestation of WNF. Genotyping of the isolated WNV RNA fragments from clinical and biological material showed that I, II and IV West Nile virus genotypes were circulating in the European part of Russia. Forecast of epidemic situation development in 2019 reveals further increase in the incidence and does not exclude the possibility of a significant localincrease of WNF incidence in certain regions of Russia. </p></trans-abstract><kwd-group xml:lang="ru"><kwd>лихорадка Западного Нила (ЛЗН )</kwd><kwd>вирус Западного Нила (ВЗН )</kwd><kwd>эпидемическая ситуация</kwd></kwd-group><kwd-group xml:lang="en"><kwd>West Nile fever (WNF)</kwd><kwd>West Nile virus (WNV)</kwd><kwd>epidemic situation</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Путинцева Е.В, Смелянский В.П., Алексейчик И.О., Бородай Н.Вh., Чеснокова С.Н., Алиева А.К., Агаркова Е.А., Батурин А.А., Викторов Д.В., Топорков А.В. Итоги мониторинга возбудителя Западного Нила в 2017 г. на территории Российской Федерации. Прогноз развития ситуации в 2018 г. в России. Проблемы особо опасных инфекций. 2018; 1:56–62. 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