<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">microbe</journal-id><journal-title-group><journal-title xml:lang="ru">Проблемы особо опасных инфекций</journal-title><trans-title-group xml:lang="en"><trans-title>Problems of Particularly Dangerous Infections</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0370-1069</issn><issn pub-type="epub">2658-719X</issn><publisher><publisher-name>Russian Research Anti-Plague Institute “Microbe”</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21055/0370-1069-2019-1-103-106</article-id><article-id custom-type="elpub" pub-id-type="custom">microbe-1131</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>Полевое эпидемиологическое исследование факторов риска заболеваемости бруцеллезом в Джалал-Абадской области Кыргызской Республики</article-title><trans-title-group xml:lang="en"><trans-title>Field Epidemiological Study of the Risk Factors of Brucellosis Insidence in the Jalal-Abad Region of Kyrgyz Republic</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Абдикаримов</surname><given-names>С. Т.</given-names></name><name name-style="western" xml:lang="en"><surname>Abdikarimov</surname><given-names>S. T.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кыргызская Республика. Кыргызская Республика, 720005, Бишкек, Скрябина, 92</p></bio><bio xml:lang="en"><p>92, Skryabina St., Bishkek, 720005, Kyrgyz Republic</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кыдышов</surname><given-names>К.</given-names></name><name name-style="western" xml:lang="en"><surname>Kydyshov</surname><given-names>K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кыргызская Республика. Кыргызская Республика, 720005, Бишкек, Скрябина, 92</p></bio><bio xml:lang="en"><p>92, Skryabina St., Bishkek, 720005, Kyrgyz Republic</p></bio><email xlink:type="simple">kydyshov80@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Усенбаев</surname><given-names>Н. Т.</given-names></name><name name-style="western" xml:lang="en"><surname>Usenbaev</surname><given-names>N. T.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кыргызская Республика. Кыргызская Республика, 720005, Бишкек, Скрябина, 92</p></bio><bio xml:lang="en"><p>92, Skryabina St., Bishkek, 720005, Kyrgyz Republic</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дуйшеналиева</surname><given-names>Э. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Duishenalieva</surname><given-names>E. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кыргызская Республика. Кыргызская Республика, 720005, Бишкек, Скрябина, 92</p></bio><bio xml:lang="en"><p>92, Skryabina St., Bishkek, 720005, Kyrgyz Republic</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Республиканский центр карантинных и особо опасных инфекций Министерства здравоохранения Кыргызской Республики</institution><country>Кыргызстан</country></aff><aff xml:lang="en"><institution>Republican Center for Quarantine and Particularly Dangerous Infectious Diseases of the Ministry of Health of the Kyrgyz Republic</institution><country>Kyrgyzstan</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>03</day><month>04</month><year>2019</year></pub-date><volume>0</volume><issue>1</issue><fpage>103</fpage><lpage>106</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Абдикаримов С.Т., Кыдышов К., Усенбаев Н.Т., Дуйшеналиева Э.М., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Абдикаримов С.Т., Кыдышов К., Усенбаев Н.Т., Дуйшеналиева Э.М.</copyright-holder><copyright-holder xml:lang="en">Abdikarimov S.T., Kydyshov K., Usenbaev N.T., Duishenalieva E.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.microbe.ru/jour/article/view/1131">https://journal.microbe.ru/jour/article/view/1131</self-uri><abstract><p>Целью данного исследования явилось определение факторов риска заболеваемости бруцеллезом в Джалал-Абадской области Кыргызской Республики. Материалы и методы. Для определения факторов риска заболеваемости бруцеллезом проведено полевое эпидемиологическое исследование методом случай-контроль. В исследовании приняли участие 180 респондентов (90 случаев и 90 контролей). Случаи бруцеллеза определены на основе эпидемиологических, клинических и лабораторных критериев. Респонденты опрашивались с использованием разработанного вопросника. Для определения меры ассоциации между воздействием и заболеванием рассчитаны соотношение шансов (OR) для каждого фактора. Результаты и обсуждение. Выявлено, что употребление непастеризованной домашней сметаны (ОR = 2,8; CI = 1,5–5,2; р = 0,0001), шашлыка (ОR = 5,1; CI = 2,5–10,4; р = 0,0001), случаи абортов или мертворождений среди животных в домашнем хозяйстве (ОR = 11,3; CI = 4,2–30,6; р = 0,0001), уборка стойла (ОR = 2,5; CI = 1,3–4,626; р = 0,0001), стрижка овец (ОR = 2,6; CI = 1,2–5,6; р = 0,01) и убой животных (ОR = 2,9; CI =1,2–6,5; р = 0,01) статистически достоверно ассоциированы с риском инфицирования бруцеллезом. Исходя из этого, названные факторы являются ведущими факторами риска инфицирования бруцеллезом. Содержание скота в частных домовладениях (ОR = 7,1; CI = 3,0–16,5; р = 0,0001) имеет также большое значение в качестве фактора риска. Значение показателя OR (ОR = 0,8; CI = 0,04–0,18; р = 0,0001) позволяет проводить целенаправленную и дифференцированную профилактику бруцеллеза. </p></abstract><trans-abstract xml:lang="en"><p>Objective of this study was to determine the risk factors of brucellosis morbidity in the Jalal-Abad Region of Kyrgyzstan. Materials and methods. A case-control study was conducted in the process of field epidemiological survey of risk factors of brucellosis incidence that lasted for 6 month in the year 2018 in the Jalal-Abad Region. The study involved 180 respondents (90 cases and 90 controls). Cases of brucellosis were identified on the basis of epidemiological, clinical and laboratory criteria. Respondents were interviewed using the developed questionnaire to obtain information on the risk factors. To determine the exposure/ disease ratio, the odds ratio (OR) was calculated for each factor. Results and discussion. It was revealed that the intake of unpasteurized homemade cream (OR = 2.8; CI = 1.5–5.2; p = 0.0001), grilled meat (shish-kebabs) (OR = 5.1; CI = 2.5–10.4; p = 0.0001); cases of abortion or stillbirth among animals in households (OR = 11.3; CI = 4.2–30.6; p = 0.0001), stall cleaning (OR = 2.5; CI = 1.3–4.626; p = 0.0001), shearing of sheep (OR = 2.6; CI = 1.2–5.6; p = 0.01) and animal slaughter (OR = 2.9; CI = 1.2–6.5; p = 0.01) are statistically significant in relation to the risk of infection with brucellosis. To that end, the listed factors are the  key risk factors for brucellosis infection. The livestock keeping in private households (OR = 7.1; CI = 3.0–16.5; p = 0.0001) is also of great importance as a risk factor. For implementation of any preventive measures against brucellosis the value of the OR indicator (OR = 0.8, CI = 0.04–0.18; p = 0.0001) proves their reasonability. </p></trans-abstract><kwd-group xml:lang="ru"><kwd>бруцеллез</kwd><kwd>факторы риска</kwd><kwd>Кыргызская Республика</kwd><kwd>Джалал-Абадская область</kwd></kwd-group><kwd-group xml:lang="en"><kwd>brucellosis</kwd><kwd>risk factor</kwd><kwd>Kyrgyzstan</kwd><kwd>Jalal-Abad Region</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Пономаренко Д.Г., Русанова Д.В., Бердникова Т.В., Хачатурова А.А., Манин Е.А., Куличенко А.Н. Обзор эпизоотологической и эпидемиологической ситуации по бруцеллезу в Российской Федерации в 2017 г. и прогноз на 2018 г. Проблемы особо опасных инфекций. 2018; 2:23–9. DOI: 10.21055/0370-1069-2018-2-23-29.</mixed-citation><mixed-citation xml:lang="en">Ponomarenko D.G., Rusanova D.V., Berdnikova Т.V., Khachaturova A.A., Manin E.A., Kulichenko A.N. [Overview of epizootiological and epidemiological situation on brucellosis in the Russian Federation in 2017 and prognosis for 2018]. Problemy Osobo Opasnykh Infektsii [Problems of Particularly Dangerous Infections]. 2018; 2:23–9. DOI: 10.21055/0370-1069-2018-2-23-29.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Closer intersectoral collaboration using existing tools can defeat zoonoses affecting humans. Geneva: WHO; 16 July, 2015. [Электронный ресурс]. URL: http: www.who.int/neglected_diseases/intersectoral_collaboration_to_defeat_zoonoses/en/ (дата обращения 23.11.2017).</mixed-citation><mixed-citation xml:lang="en">Closer inter-sectoral collaboration using existing tools can defeat zoonoses affecting humans. Geneva: WHO, 16 July, 2015. Intrnet]. (Cited 23 Nov 2017). Available from: http:www.who.int/neglected_diseases/intersectoral_collaboration_to_defeat_zoonoses/en/.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Лямкин Г.И., Пономаренко Д.Г., Худолеев А.А., Вилинская С.В., Зайцев А.А., Куличенко А.Н. Эпидемическая ситуация по бруцеллезу в Российской Федерации и государствах-участниках Содружества Независимых Государств. Инфекционные болезни: новости, мнения, обучение. 2016; 1:68–74.</mixed-citation><mixed-citation xml:lang="en">Lyamkin G.I., Ponomarenko D.G., Khudoleev A.A., Vilinskaya S.V., Zaitsev A.A., Kulichenko A.N. [Epidemic situation on brucellosis in the Russian Federation and member-state of the Commonwealth of Independent States]. Infektsionnye Bolezni: Novosti, Mneniya, Obuchenie. 2016; 1:68–74.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Bonfoh B., Kasymbekov J., Dürr S., Toktobaev N., Doherr M.G., Schueth T., Zinsstag J., Schelling E. Representative seroprevalences of brucellosis in humans and livestock in Kyrgyzstan. EcoHealth. 2012; 9(2):132–8. DOI: 10.1007/s10393-011-0722-x.</mixed-citation><mixed-citation xml:lang="en">Bonfoh B., Kasymbekov J., Dürr S., Toktobaev N., Doherr M.G., Schueth T., Zinsstag J., Schelling E. Representative seroprevalences of brucellosis in humans and livestock in Kyrgyzstan. EcoHealth. 2012; 9(2):132–8. DOI: 10.1007/s10393-011-0722-x.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Kozukeev T.B., Ajeilat S., Maes E., Favorov M., Centers for Disease Control, Prevention (CDC). Risk factors for brucellosis – Leylek and Kadamjay districts, Batken Oblast, Kyrgyzstan, January–November, 2003. MMWR Suppl.. 2006; 55(1):31–4. PMID: 16645580.</mixed-citation><mixed-citation xml:lang="en">Kozukeev T.B., Ajeilat S., Maes E., Favorov M., Centers for Disease Control, Prevention (CDC). Risk factors for brucellosis – Leylek and Kadamjay districts, Batken Oblast, Kyrgyzstan, January–November, 2003. MMWR Suppl.. 2006; 55(1):31–4. PMID: 16645580.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Husseini A.S., Ramlawi A.M. Brucellosis in the West Bank, Palestine. Saudi Med. J. 2004; 25(11):1640–3. PMID: 15573193.</mixed-citation><mixed-citation xml:lang="en">Husseini A.S., Ramlawi A.M. Brucellosis in the West Bank, Palestine. Saudi Med. J. 2004; 25(11):1640–3. PMID: 15573193.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Sofian M., Aghakhani A., Velayati A.A., Banifazl M., Eslamifar A., Ramezani A. Risk factors for human brucellosis in Iran: a case-control study. Int. J. Infect. Dis. 2008. 12(2):157–61. DOI: 10.1016/j.ijid.2007.04.019.</mixed-citation><mixed-citation xml:lang="en">Sofian M., Aghakhani A., Velayati A.A., Banifazl M., Eslamifar A., Ramezani A. Risk factors for human brucellosis in Iran: a case-control study. Int. J. Infect. Dis. 2008. 12(2):157–61. DOI: 10.1016/j.ijid.2007.04.019.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
