<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">microbe</journal-id><journal-title-group><journal-title xml:lang="ru">Проблемы особо опасных инфекций</journal-title><trans-title-group xml:lang="en"><trans-title>Problems of Particularly Dangerous Infections</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0370-1069</issn><issn pub-type="epub">2658-719X</issn><publisher><publisher-name>Russian Research Anti-Plague Institute “Microbe”</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21055/0370-1069-2014-1-83-86</article-id><article-id custom-type="elpub" pub-id-type="custom">microbe-116</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ЭПИДЕМИОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>EPIDEMIOLOGY</subject></subj-group></article-categories><title-group><article-title>Эпидемиологическая характеристика энтеровирусной инфекции в Хабаровском крае в условиях чрезвычайной гидрологической ситуации</article-title><trans-title-group xml:lang="en"><trans-title>Epidemiological Characteristics of Enterovirus Infection in the Khabarovsk Territory under Hydrologic Emergency Situation</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Троценко</surname><given-names>О. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Trotsenko</surname><given-names>O. E.</given-names></name></name-alternatives><email xlink:type="simple">bovlad@email.kht.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Отт</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Ott</surname><given-names>V. A.</given-names></name></name-alternatives><email xlink:type="simple">root@sanepid.khv.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Онищенко</surname><given-names>Г. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Onishchenko</surname><given-names>G. G.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Каравянская</surname><given-names>Т. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Karavyanskaya</surname><given-names>T. N.</given-names></name></name-alternatives><email xlink:type="simple">root@sanepid.khv.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гарбуз</surname><given-names>Ю. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Garbuz</surname><given-names>Yu. A.</given-names></name></name-alternatives><email xlink:type="simple">glbuh@gorses.khv.ru</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сапега</surname><given-names>Е. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Sapega</surname><given-names>E. Yu.</given-names></name></name-alternatives><email xlink:type="simple">bovlad@email.kht.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зайцева</surname><given-names>Т. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Zaitseva</surname><given-names>T. A.</given-names></name></name-alternatives><email xlink:type="simple">root@sanepid.khv.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Присяжнюк</surname><given-names>Е. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Prisyazhnyuk</surname><given-names>E. N.</given-names></name></name-alternatives><email xlink:type="simple">glbuh@gorses.khv.ru</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Резник</surname><given-names>В. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Reznik</surname><given-names>V. I.</given-names></name></name-alternatives><email xlink:type="simple">glbuh@gorses.khv.ru</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Корита</surname><given-names>Т. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Korita</surname><given-names>T. V.</given-names></name></name-alternatives><email xlink:type="simple">bovlad@email.kht.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лебедева</surname><given-names>Л. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Lebedeva</surname><given-names>L. A.</given-names></name></name-alternatives><email xlink:type="simple">glbuh@gorses.khv.ru</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Голубева</surname><given-names>Е. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Golubeva</surname><given-names>E. M.</given-names></name></name-alternatives><email xlink:type="simple">root@sanepid.khv.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Котова</surname><given-names>В. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Kotova</surname><given-names>V. O.</given-names></name></name-alternatives><email xlink:type="simple">bovlad@email.kht.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бутакова</surname><given-names>Л. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Butakova</surname><given-names>L. V.</given-names></name></name-alternatives><email xlink:type="simple">bovlad@email.kht.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Балахонцева</surname><given-names>Л. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Balakhontseva</surname><given-names>L. A.</given-names></name></name-alternatives><email xlink:type="simple">bovlad@email.kht.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Атаманчук</surname><given-names>И. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Atamanchuk</surname><given-names>I. L.</given-names></name></name-alternatives><email xlink:type="simple">glbuh@gorses.khv.ru</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Балахонов</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Balakhonov</surname><given-names>S. V.</given-names></name></name-alternatives><email xlink:type="simple">adm@chumin.irkutsk.ru</email><xref ref-type="aff" rid="aff-5"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Носков</surname><given-names>А. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Noskov</surname><given-names>A. K.</given-names></name></name-alternatives><email xlink:type="simple">adm@chumin.irkutsk.ru</email><xref ref-type="aff" rid="aff-5"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Севостьянова</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Sevost’Yanova</surname><given-names>A. V.</given-names></name></name-alternatives><email xlink:type="simple">adm@chumin.irkutsk.ru</email><xref ref-type="aff" rid="aff-5"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Хабаровский научно-исследовательский институт эпидемиологии и микробиологии</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Khabarovsk Research Institute of Epidemiology and Microbiology</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Управление Роспотребнадзора по Хабаровскому краю</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Rospotrebnadzor Administration in the Khabarovsk Territory</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Федеральная служба по надзору в сфере защиты прав потребителей и благополучия человека</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal Service for Surveillance in the Sphere of Consumers Rights Protection and Human Welfare</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>Центр гигиены и эпидемиологии в Хабаровском крае</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Center of Hygiene and Epidemiology in the Khabarovsk Territory</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-5"><aff xml:lang="ru"><institution>Иркутский научно-исследовательский противочумный институт</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Irkutsk Research Anti-Plague Institute of Siberia and Far East</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2014</year></pub-date><pub-date pub-type="epub"><day>20</day><month>03</month><year>2014</year></pub-date><volume>0</volume><issue>1</issue><fpage>83</fpage><lpage>86</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Троценко О.Е., Отт В.А., Онищенко Г.Г., Каравянская Т.Н., Гарбуз Ю.А., Сапега Е.Ю., Зайцева Т.А., Присяжнюк Е.Н., Резник В.И., Корита Т.В., Лебедева Л.А., Голубева Е.М., Котова В.О., Бутакова Л.В., Балахонцева Л.А., Атаманчук И.Л., Балахонов С.В., Носков А.К., Севостьянова А.В., 2014</copyright-statement><copyright-year>2014</copyright-year><copyright-holder xml:lang="ru">Троценко О.Е., Отт В.А., Онищенко Г.Г., Каравянская Т.Н., Гарбуз Ю.А., Сапега Е.Ю., Зайцева Т.А., Присяжнюк Е.Н., Резник В.И., Корита Т.В., Лебедева Л.А., Голубева Е.М., Котова В.О., Бутакова Л.В., Балахонцева Л.А., Атаманчук И.Л., Балахонов С.В., Носков А.К., Севостьянова А.В.</copyright-holder><copyright-holder xml:lang="en">Trotsenko O.E., Ott V.A., Onishchenko G.G., Karavyanskaya T.N., Garbuz Y.A., Sapega E.Y., Zaitseva T.A., Prisyazhnyuk E.N., Reznik V.I., Korita T.V., Lebedeva L.A., Golubeva E.M., Kotova V.O., Butakova L.V., Balakhontseva L.A., Atamanchuk I.L., Balakhonov S.V., Noskov A.K., Sevost’Yanova A.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.microbe.ru/jour/article/view/116">https://journal.microbe.ru/jour/article/view/116</self-uri><abstract><p>В работе показана роль паводка в изменении эпидемиологической ситуации по энтеровирусным инфекциям в 2013 г. в Хабаровском крае. Заболеваемость энтеровирусной инфекцией в Хабаровском крае в 2013 г. характеризовалась значительным повышением показателей еще в период до наступления паводка. В недельной динамике уровней заболеваемости среди совокупного населения отмечено два пиковых подъема с более интенсивным и совпадающим с началом паводковой ситуации вторым. Для эпидемического процесса характерны изменения в возрастной и клинической структуре заболевших. Доля больных энтеровирусной инфекцией, пострадавших в период наводнения в очагах групповой заболеваемости, а также удельный вес заболевших вследствие возможного воздействия паводковой ситуации при их проживании в зонах подтопления, оказались в Хабаровском крае незначительными. Выявлена высокая степень гетерогенности циркулирующих в 2013 г. штаммов энтеровирусов, особенно завозных из стран Азиатско-Тихоокеанского региона и не характерных для Хабаровского края вирусов группы Коксаки А, возможно обусловивших неблагоприятную эпидемиологическую ситуацию по энтеровирусной инфекции в 2013 г. независимо от паводковой ситуации.</p></abstract><trans-abstract xml:lang="en"><p>The paper contains the data on the role of high waters (2013) in changing epidemiological situation on enterovirus infections in the Khabarovsk Territory. The incidence rate in the region was characterized by the significant increase even before the flood, 2013. Thus, two peaks of enterovirus morbidity curve were identified for the period of a week: one - more intensive, another - coincident with flood outbreak. Enterovirus epidemiological process was notified by the changes in clinical picture among the infected population and cohort age-related structure. The percentage of the patients with enterovirus infections in the foci clusters and the index of people infected due to possible exposure to shattering impact of the flood, turned out to be low. However, revealed was high rate of heterogeneity of the circulating enterovirus strains, non-specific for the Khabarovsk territory and mostly originating from countries of Asia-Pacific region - coxsackie A viruses, which might stand for a possible cause of unfavorable epidemiological situation in 2013.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>паводок</kwd><kwd>Хабаровский край</kwd><kwd>энтеровирусная инфекция</kwd><kwd>эпидемический процесс</kwd><kwd>очаги заболеваемости</kwd><kwd>пострадавшее население</kwd><kwd>flood</kwd><kwd>the Khabarovsk Territory</kwd><kwd>enterovirus infection</kwd><kwd>epidemiological process</kwd><kwd>morbidity foci</kwd><kwd>affected population</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Брюханова Г.Д., Грижебовский Г.М., Мезенцев В.М. Гидрологические опасные природные явления как причина осложнения эпидемиологической обстановки. Журн. микробиол., эпидемиол. и иммунобиол. 2003; 6 (Приложение):81-6.</mixed-citation><mixed-citation xml:lang="en">Bryukhanova G.D., Grizhebovsky G.M., Mezentsev V.M. [Hazardous hydrological natural phenomena as a cause of aggravation of epidemiological situation]. Zh. Mikrobiol. Epidemiol. Immunobiol. 2003; 6(Appendix):81–6.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Новик Е.С., Резник В.И., Каравянская Т.Н., Перескокова М.А., Лебедева Л.А., Исаева И.В., Савосина Л.В., Чистяк В.М., Бондаренко А.П., Троценко О.Е., Отт В.А., Маслов Д.В., Андреева Г.В., Баранов Н.И., Гореликов В.И., Лукашев А.Н. Значимость водного фактора в возникновении вспышек энтеровирусной инфекции на территории Хабаровского края и Приморья. Дальневосточный журн. инф. патологии. 2009; 14:6-13.</mixed-citation><mixed-citation xml:lang="en">Novik E.S., Reznik V.I., Karavyanskaya T.N., Pereskokova M.A., Lebedeva L.A., Isaeva I.V., Savosina L.V., Chistyak V.M., Bondarenko A.P., Trotsenko O.E., Ott V.A., Maslov D.V., Andreeva G.V., Baranov N.I., Gorelikov V.I., Lukashev A.N. [Significance of hydrological/water factor for the emergence of enterovirus infection outbreaks in the Khabarovsk and the Amur-Region Territories]. Dal’nevost. Zh. Infek. Patologii. 2009; 14:6–13.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Сапега Е.Ю., Троценко О.Е., Резник В.И., Отт В.А., Каравянская Т.Н., Голубева Е.М. Эпидемический процесс энтеровирусной инфекции в Дальневосточном федеральном округе в 2011 г. Инф. и иммунитет. 2012; 2(1-2):536.</mixed-citation><mixed-citation xml:lang="en">Sapega E.YU., Trotsenko O.E., Reznik V.I., Ott V.A., Karavyanskaya T.N., Golubeva E.M. [Epidemic process of enterovirus infection in the Far East Constituent Entity in 2011]. Infection and immunity. 2012; 2(1–2):536.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Троценко О.Е., Лукашев А.Н., Сапега Е.Ю., Резник В.И., Каравянская Т.Н., Котова В.О., Балахонцева Л.А., Худякова Л.В., Амяга Е.Н., Корита П.В. Организация молекулярно-эпидемиологического мониторинга энтeровирусных инфекций в Дальневосточном ФО РФ. Дальневосточный журн. инф. патологии. 2011; 19:5-12.</mixed-citation><mixed-citation xml:lang="en">Trotsenko O.E., Lukashev A.N., Sapega E.Yu., Rezhik V.I., Karavyanskaya T.N., Kotova V.O., Balakhontseva L.A., Khudyakova L.V., Amyaga E.N., Korita P.V. [Management of epidemiological monitoring over enterovirus infections in the Far East Constituent Entity of the Russian Federation]. Dal’nevost. Zh. Infek. Patologii. 2011; 19:5–12.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Троценко О.Е., Лукашев А.Н., Каравянская Т.Н., Резник В.И., Сапега Е.Ю., Котова В.О., Амяга Е.Н., П.В. Корита. Молекулярно-эпидемиологический мониторинг циркуляции энтеровирусов на Дальнем Востоке и в Забайкалье. Журн. микробиол., эпидемиол. и иммунобиол. 2013; 1:70-5.</mixed-citation><mixed-citation xml:lang="en">Trotsenko O.E., Lukashev A.N., Karavyanskaya T.N., Rezhik V.I., Sapega E.Yu., Kotova V.O., Amyaga E.N., Korita P.V. [Molecularepidemiological monitoring over circulation of enteroviruses in the Far East and Trans-Baikal regions]. Zh. Mikrobiol. Epidemiol. Immunobiol. 2013; 1:70–5.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">He Y.Q., Chen L., Xu W.B., Yang H., Wang H.Z., Zong W.P., Xian H.X., Chen H.L., Yao X.J., Hu Z.L., Luo M., Zhang H.L., Ma H.W., Cheng J.Q., Feng Q.J., Zhao D.J. Emergence, circulation, and spatiotemporal phylogenetic analysis of coxsackievirus a6- and coxsackievirus a10-associated hand, foot, and mouth disease infections from 2008 to 2012 in Shenzhen, China. J. Clin. Microbiol. 2013; 51(11):3560-6.</mixed-citation><mixed-citation xml:lang="en">He Y.Q., Chen L., Xu W.B., Yang H., Wang H.Z., Zong W.P., Xian H.X., Chen H.L., Yao X.J., Hu Z.L., Luo M., Zhang H.L., Ma H.W., Cheng J.Q., Feng Q.J., Zhao D.J. Emergence, circulation, and spatiotemporal phylogenetic analysis of coxsackievirus a6- and coxsackievirus a10-associated hand, foot, and mouth disease infections from 2008 to 2012 in Shenzhen, China. J. Clin. Microbiol. 2013; 51(11):3560–6.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Puenpa J., Chieochansin T., Linsuwanon P., Korkong S., Thongkomplew S., Vichaiwattana P., Theamboonlers A., Poovorawan Y. Hand, foot, and mouth disease caused by coxsackievirus A6, Thailand, 2012. Emerg. Infect. Dis. 2013; 19(4):641-3.</mixed-citation><mixed-citation xml:lang="en">Puenpa J., Chieochansin T., Linsuwanon P., Korkong S.,</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Thongkomplew S., Vichaiwattana P., Theamboonlers A., Poovorawan Y. Hand, foot, and mouth disease caused by coxsackievirus A6, Thailand, 2012. Emerg. Infect. Dis. 2013; 19(4):641–3.</mixed-citation><mixed-citation xml:lang="en">Thongkomplew S., Vichaiwattana P., Theamboonlers A., Poovorawan Y. Hand, foot, and mouth disease caused by coxsackievirus A6, Thailand, 2012. Emerg. Infect. Dis. 2013; 19(4):641–3.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
