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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">microbe</journal-id><journal-title-group><journal-title xml:lang="ru">Проблемы особо опасных инфекций</journal-title><trans-title-group xml:lang="en"><trans-title>Problems of Particularly Dangerous Infections</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0370-1069</issn><issn pub-type="epub">2658-719X</issn><publisher><publisher-name>Russian Research Anti-Plague Institute “Microbe”</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21055/0370-1069-2020-2-108-114</article-id><article-id custom-type="elpub" pub-id-type="custom">microbe-1334</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>Дифференциация территории Забайкальского края по заболеваемости клещевым вирусным энцефалитом</article-title><trans-title-group xml:lang="en"><trans-title>Differentiation of Transbaikal Territory by Tick-Borne Viral Encephalitis Incidence</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Туранов</surname><given-names>А. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Turanov</surname><given-names>A. O.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><email xlink:type="simple">cge@megalink.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3918-7832</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Никитин</surname><given-names>А. Я.</given-names></name><name name-style="western" xml:lang="en"><surname>Nikitin</surname><given-names>A. Ya.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Никитин Алексей Яковлевич</p><p>664047, Иркутск, ул. Трилиссера, 78</p></bio><bio xml:lang="en"><p>Aleksey Ya. Nikitin</p><p>78, Trilissera St., Irkutsk, 664047</p></bio><email xlink:type="simple">nikitin_irk@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6612-479X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Андаев</surname><given-names>Е. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Andaev</surname><given-names>E. I.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><email xlink:type="simple">adm@chumin.irkutsk.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4201-5828</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Балахонов</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Balakhonov</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><email xlink:type="simple">adm@chumin.irkutsk.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2537-8926</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шашина</surname><given-names>Н. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Shashina</surname><given-names>N. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>117246, Москва, Научный проезд, 18.</p></bio><bio xml:lang="en"/><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">ФБУЗ «Центр гигиены и эпидемиологии в Забайкальском крае»<country>Россия</country></aff><aff xml:lang="en">Center of Hygiene and Epidemiology in Transbaikal Territory<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru">ФКУЗ «Иркутский научно-исследовательский противочумный институт»<country>Россия</country></aff><aff xml:lang="en">Irkutsk Research Anti-Plague Institute<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru">ФБУН «Научно-исследовательский институт Дезинфектологии»<country>Россия</country></aff><aff xml:lang="en">Research Institute of Disinfectology<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>12</day><month>07</month><year>2020</year></pub-date><volume>0</volume><issue>2</issue><fpage>108</fpage><lpage>114</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Туранов А.О., Никитин А.Я., Андаев Е.И., Балахонов С.В., Шашина Н.И., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Туранов А.О., Никитин А.Я., Андаев Е.И., Балахонов С.В., Шашина Н.И.</copyright-holder><copyright-holder xml:lang="en">Turanov A.O., Nikitin A.Y., Andaev E.I., Balakhonov S.V., Shashina N.I.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.microbe.ru/jour/article/view/1334">https://journal.microbe.ru/jour/article/view/1334</self-uri><abstract><p>Цель исследования – провести дифференциацию административных районов Забайкальского края в период спада заболеваемости клещевым вирусным энцефалитом (КВЭ) на группы эпидемиологического риска и охарактеризовать их по объему мер специфической и неспецифической профилактики.</p><sec><title>Материалы и методы</title><p>Материалы и методы. Ретроспективный анализ эпидемиологической обстановки по КВЭ основан на данных формы № 2 статистической отчетности «Сведения об инфекционных и паразитарных заболеваниях» за 2009–2019 гг. и других материалах Управления Роспотребнадзора по Забайкальскому краю. Путем расчета 95 % доверительного интервала для среднемноголетних показателей числа случаев КВЭ за 10-летний период в муниципальных образованиях края и оценки принадлежности отклоняющихся значений к исследуемой совокупности проведена разбивка районов на группы с различным уровнем эпидемиологического риска.</p></sec><sec><title>Результаты и обсуждение</title><p>Результаты и обсуждение. Из 32 районов Забайкальского края 24 являются эндемичными по КВЭ. Последние разделены на пять групп: с очень высоким показателем эпидемиологического риска (2 района), с высоким (5), средним (8) и низким (8), а также административный центр субъекта, который по всему комплексу показателей (проявление болезни, плотность населения, факторы направленного снижения КВЭ, социально-бытовые и экономические условия) не может рассматриваться совместно с другими МО. Каждая группа районов охарактеризована по числу случаев и инцидентности КВЭ, обращаемости людей, пострадавших от присасывания клещей, в медицинские организации, объемам вакцинации, серопрофилактики, площадям акарицидных обработок. Даны рекомендации по необходимому комплексу и объемам мер профилактики КВЭ в группах административных районов, различающихся по уровню эпидемиологического риска.</p></sec></abstract><trans-abstract xml:lang="en"><p>Objective of the study was to differentiate the Administrative Districts of theTransbaikalTerritory at the time of Tick-borne viral encephalitis (TBVE) incidence recession by epidemiological risk groups and to characterize them by volume of specific and nonspecific preventive measures.</p><sec><title>Materials and methods</title><p>Materials and methods. Retrospective analysis of TBVE epidemiological situation is based on the statistical reporting data “Information on infectious and parasitic diseases” in 2009–2019 and other materials of the Rospotrebnadzor Administration in the Transbaikal Territory. The clustering of areas with various levels of epidemiological risk was conducted by calculation of 95 % confidential interval for long-term annual average of TBVE cases in municipal units of the Territory over a decade and assessment of appurtenance of the deviating values to the aggregate under study.</p></sec><sec><title>Results and discussion</title><p>Results and discussion. Twenty four out of 32 districts of the Transbaikal Territory are endemic for TBVE. These areas are divided into five groups: with very high epidemiological risk (2 districts), high (5), medium (8), and low (8) risk respectively, as well as the administrative center of the constituent entity which by the whole complex of indicators (disease manifestation, population density, factors of targeted TBVE decrease, social-and-living and economical conditions) cannot be considered together with the rest of municipalities. Each group of the districts was characterized by the number of cases and TBVE incidence rates, medical aid seeking by persons who suffered from tick bites, vaccination volumes, seroprevention, areas of acaricide treatments. Recommendations are presented for the essential complex and scope of measures to prevent TBVE in the groups of administrative districts that differ by the level of epidemiological risk.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>клещевой вирусный энцефалит</kwd><kwd>заболеваемость</kwd><kwd>дифференциация территорий</kwd><kwd>эпидемиологические риски</kwd></kwd-group><kwd-group xml:lang="en"><kwd>tick-borne viral encephalitis</kwd><kwd>incidence</kwd><kwd>differentiation of territories</kwd><kwd>epidemiological risks</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Злобин В.И., Рудаков Н.В., Малов И.В. Клещевые трансмиссивные инфекции. Новосибирск: Наука; 2015. 224 с.</mixed-citation><mixed-citation xml:lang="en">Zlobin   V.I.,   Rudakov   N.V.,   Malov   I.V.   [Tick-borne Transmissible Infections]. Novosibirsk: “Nauka”; 2015. 224 p.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Чернохаева Л.Л., Холодилов И.С., Пакскина Н.Д. Современный ареал клещевого энцефалита в Российской Федерации. Труды института полиомиелита и вирусных энцефалитов имени М.П. Чумакова РАМН. Медицинская вирусология. 2016; 30(1):6–22.</mixed-citation><mixed-citation xml:lang="en">, Chernokhaeva L.L., Kholodilov I.S., Pakskina N.D. [Current distribution area of tick-borne encephalitis in the Russian Federation]. Trudy Instituta Poliomielita i Virusnykh Entsefalitov Imeni M.P. Chumakova RAMN. Meditsinskaya Virusologiya [Proceedings of the Institute of Poliomyelitis and Viral Encephalitis Named after M.P. Chumakov, RAMS. Medical Virology]. 2016; 1:6–22.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Dobler G., Erber W., Schmitt H.-J., editors. The TBE book. Singapore: Global Health Press; 2018. 304 р.</mixed-citation><mixed-citation xml:lang="en">Dobler G., Erber W., Schmitt H.-J., editors. The TBE book. Singapore: Global Health Press; 2018. 304 р.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Valarcher J.F., Hдgglund S., Juremalm M., Blomqvist G., Renstrцm L., Zohari S., Leijon M., Chirico J. Tick-borne encephalitis. Rev. Sci. Tech. 2015; 34(2):453–66. DOI: 10.20506/rst.34.2.2371.</mixed-citation><mixed-citation xml:lang="en">Valarcher J.F., Hдgglund S., Juremalm M., Blomqvist G., Renstrцm L., Zohari S., Leijon M., Chirico J. Tick-borne encephalitis. Rev. Sci. Tech. 2015; 34(2):453–66. DOI: 10.20506/rst.34.2.2371.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Ruo-Xi Sun, Sheng-Jie Lai, Yang Yang, Xin-Lou Li, Kun Liu, Hong-Wu Yao, Hang Zhou, Yu Li, Li-Ping Wang, Di Mu, WenWu Yin, Li-Qun Fang, Hong-Jie Yu, Wu-Chun Cao. Mapping the distribution of tick-borne encephalitis in mainland China. Ticks Tick borne Dis. 2017; 8(4):631–39. DOI: 10.1016/j.ttbdis.2017.04.009.</mixed-citation><mixed-citation xml:lang="en">Ruo-Xi Sun, Sheng-Jie Lai, Yang Yang, Xin-Lou Li, Kun Liu, Hong-Wu Yao, Hang Zhou, Yu Li, Li-Ping Wang, Di Mu, WenWu Yin, Li-Qun Fang, Hong-Jie Yu, Wu-Chun Cao. Mapping the distribution of tick-borne encephalitis in mainland China. Ticks Tick borne Dis. 2017; 8(4):631–39. DOI: 10.1016/j.ttbdis.2017.04.009.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Hay S.I., Tatem A.J., Graham A.J., Goetz S.J., Rogers D.J. Global environmental data for mapping infectious disease distribution. Adv. Parasitol. 2006; 62:37–77. DOI: 10.1016/S0065308X(05)62002-7.</mixed-citation><mixed-citation xml:lang="en">Hay S.I., Tatem A.J., Graham A.J., Goetz S.J., Rogers D.J. Global environmental data for mapping infectious disease distribution. Adv. Parasitol. 2006; 62:37–77. DOI: 10.1016/S0065308X(05)62002-7.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Jaenson T.J.T., Jensen J.K. Records of ticks (Acari, Ixodidae) from the Faroe Islands. Norw. J. Entomol. 2007; 54:11–5.</mixed-citation><mixed-citation xml:lang="en">Jaenson T.J.T., Jensen J.K. Records of ticks (Acari, Ixodidae) from the Faroe Islands. Norw. J. Entomol. 2007; 54:11–5.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Randolph S.E., Rogers D.J. Tick-borne disease systems: mapping geographic and phylogenetic space. Adv. Parasitol. 2006; 62:263–91. DOI: 10.1016/S0065-308X(05)62008-8.</mixed-citation><mixed-citation xml:lang="en">Randolph S.E., Rogers D.J. Tick-borne disease systems: mapping geographic and phylogenetic space. Adv. Parasitol. 2006; 62:263–91. DOI: 10.1016/S0065-308X(05)62008-8.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Riccardi N., Antonello R.M., Luzzati R., Zajkowska J., Di Bella S., Giacobbe D.R. Tick-borne encephalitis in Europe: a brief update on epidemiology, diagnosis, prevention, and treatment. Eur. J. Intern. Med. 2019; 62:1–6. DOI: 10.1016/j.ejim.2019.01.004.</mixed-citation><mixed-citation xml:lang="en">Riccardi N., Antonello R.M., Luzzati R., Zajkowska J., Di Bella S., Giacobbe D.R. Tick-borne encephalitis in Europe: a brief update on epidemiology, diagnosis, prevention, and treatment. Eur. J. Intern. Med. 2019; 62:1–6. DOI: 10.1016/j.ejim.2019.01.004.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Ruzek D., Avљiи Ћupanc T., Borde J., Chrdle A., Eyer L., Karganova G., Kholodilov I., Knap N., Kozlovskaya L., Matveev A., Miller A. D., Osolodkin D. I., Цverby A. K., Tikunova N., Tkachev S., Zajkowska Ruzek D., Avљiи Ћupanc T., Borde J., Chrdle A., Eyer L., Karganova G., Kholodilov I., Knap N., Kozlovskaya L., Matveev A., Miller A. D., Osolodkin D. I., Цverby A. K., Tikunova N., Tkachev S., Zajkowska J. Tick-borne encephalitis in Europe and Russia: Review of pathogenesis, clinical features, therapy, and vaccines. Antiviral Res. 2019; 164:23–51. DOI: 10.1016/j.antiviral.2019.01.014.</mixed-citation><mixed-citation xml:lang="en">Ruzek D., Avљiи Ћupanc T., Borde J., Chrdle A., Eyer L., Karganova G., Kholodilov I., Knap N., Kozlovskaya L., Matveev A., Miller A. D., Osolodkin D. I., Цverby A. K., Tikunova N., Tkachev S., Zajkowska J. Tick-borne encephalitis in Europe and Russia: Review of pathogenesis, clinical features, therapy, and vaccines. Antiviral Res. 2019; 164:23–51. DOI: 10.1016/j.antiviral.2019.01.014.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Носков А.К., Никитин А.Я., Андаев Е.И., Пакскина Н.Д., Яцменко Е.В., Веригина Е.В., Иннокентьева Т.И., Балахонов С.В. Клещевой вирусный энцефалит в Российской Федерации: особенности эпидемического процесса в период устойчивого спада заболеваемости, эпидемиологическая ситуация в 2016 г., прогноз на 2017 г. Проблемы особо опасных инфекций. 2017; 1:37–43. DOI: 10.21055/0370-1069-2017-1-37-43.</mixed-citation><mixed-citation xml:lang="en">Noskov A.K., Nikitin A.Ya, Andaev E.I., Pakskina N.D, Yatsmenko E.V., Verigina E.V., Innokent’eva I.I., Balakhonov S.V. [Tick-borne virus encephalitis in the Russian Federation: features of epidemic process in steady morbidity decrease period. Epidemiological condition in 2016 and the forecast for 2017]. Problemy Osobo Opasnykh Infektsii [Problems of Particularly Dangerous Infections]. 2017; 1: 37–43. DOI: 10.21055/0370-1069 -2017-1-37-43.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Рудаков Н.В., Пеньевская Н.А., Савельев Д.А., Рудакова С.А., Штрек С.В., Андаев Е.И., Балахонов С.В. Дифференциация эндемичных территорий по уровням заболеваемости клещевыми трансмиссивными инфекциями как основа выбора стратегии и тактики профилактики. Здоровье населения и среда обитания. 2019; 12:56–61. DOI: 10.35627/2219-5238/2019-321-12-56-61.</mixed-citation><mixed-citation xml:lang="en">Rudakov N.V., Pen’evskaya N.A., Savel’ev D.A., Rudakova S.A., Shtrek S.V., Andaev E.I., Balakhonov S.V. [Differentiation of endemic areas by the levels of morbilities of tick-borne infections as the basis for the choice of prevention strategy and tactics]. Zdorovie Naseleniya i Sreda Obitaniya [Population health and Life Environment]. 2019; 12:56–61.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Ильин В.П., Андаев Е.И., Балахонов С.В., Носков А.К., Туранов А.О. Алгоритм классификации муниципальных образований субъекта Российской Федерации, основанный на оценке доверительного интервала заболеваемости клещевым вирусным энцефалитом (на примере Забайкальского края). Acta Biomedica Scientifica. 2013; 6:115–21.</mixed-citation><mixed-citation xml:lang="en">Iljin V.P., Andaev E.I., Balakhonov S.V., Noskov A.K., Turanov A.O. [Algorithm classification of municipal unions of the Russian Federation region based on a confidential interval estimation of tick-borne encephalitis virus incidence (Transbaikal krai as an example)]. Acta Biomedica Scientifica. 2013; 6:115–21.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Терентьев П.В., Ростова Н.С. Практикум по биометрии. Учебное пособие. Л.: Изд-во Ленинградского университета; 1977. 152 с.</mixed-citation><mixed-citation xml:lang="en">Terentiev P.V., Rostova N.S. [Workshop on Biometry. Handbook]. Leningrad: Publishing house of the Leningrad University; 1977. 152 p.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Ивантер Э.В., Коросов А.В. Элементарная биометрия. Петрозаводск: ПетрГУ; 2013. 110 с.</mixed-citation><mixed-citation xml:lang="en">Ivanter E.V., Korosov A.V. [Elementary Biometry]. Petrozavodsk: “PetrGU”; 2013. 110 p.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Савилов Е.Д., Астафьев В.А., Жданова С.Н., Заруднев Е.А. Эпидемиологический анализ: Методы статистической обработки материала. Новосибирск: Наука-Центр; 2011. 156 с.</mixed-citation><mixed-citation xml:lang="en">Savilov E.D., Astaf’ev V.A., Zhdanova S.N., Zarudnev E.A. [Epidemiological Analysis: Methods of Statistical Processing of a Material]. Novosibirsk: “Nauka-Tsentr”; 2011. 156 p.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Успенский И.В. Кровососущие клещи (Acarina, Ixodoidea) как существенный компонент городской среды. Зоологический журнал. 2017; 96(8): 871–98.</mixed-citation><mixed-citation xml:lang="en">Uspensky I.V. [Blood-sucking ticks (Acarina, Ixodoidea) as an essential component of the urban environment]. Zoologichesky Zhurnal [Russian Journal of Zoology]. 2017; 8(96):871–98</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
