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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">microbe</journal-id><journal-title-group><journal-title xml:lang="ru">Проблемы особо опасных инфекций</journal-title><trans-title-group xml:lang="en"><trans-title>Problems of Particularly Dangerous Infections</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0370-1069</issn><issn pub-type="epub">2658-719X</issn><publisher><publisher-name>Russian Research Anti-Plague Institute “Microbe”</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21055/0370-1069-2020-3-27-35</article-id><article-id custom-type="elpub" pub-id-type="custom">microbe-1360</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>Гендерно-возрастная характеристика пациентов с COVID-19 на разных этапах эпидемии в Москве</article-title><trans-title-group xml:lang="en"><trans-title>Gender-Age Distribution of Patients with COVID-19 at Different Stages of Epidemic in Moscow</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4228-9044</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Акимкин</surname><given-names>В. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Akimkin</surname><given-names>V. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Российская Федерация, 111123, Москва, ул. Н овогиреевская, 3а</p></bio><bio xml:lang="en"><p>3a, Novogireevskaya St., Moscow, 111123, Russian Federation</p></bio><email xlink:type="simple">crie@pcr.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0616-9777</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кузин</surname><given-names>С. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Kuzin</surname><given-names>S. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Российская Федерация, 111123, Москва, ул. 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Гамалеи, 18</p></bio><bio xml:lang="en"><p>18, Gamaleya St., Moscow, 123098, Russian Federation</p></bio><email xlink:type="simple">semenenko@gamaleya.org</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3612-1889</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Плоскирева</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Ploskireva</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Российская Федерация, 111123, Москва, ул. 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Н овогиреевская, 3а</p></bio><bio xml:lang="en"><p>3a, Novogireevskaya St., Moscow, 111123, Russian Federation</p></bio><email xlink:type="simple">crie@pcr.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5344-5829</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чурилова</surname><given-names>Н. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Churilova</surname><given-names>N. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Российская Федерация, 111123, Москва, ул. 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Н овогиреевская, 3а</p></bio><bio xml:lang="en"><p>3a, Novogireevskaya St., Moscow, 111123, Russian Federation</p></bio><email xlink:type="simple">crie@pcr.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0803-5630</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Остроушко</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Ostroushko</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Российская Федерация, 111123, Москва, ул. Н овогиреевская, 3а</p></bio><bio xml:lang="en"><p>3a, Novogireevskaya St., Moscow, 111123, Russian Federation</p></bio><email xlink:type="simple">crie@pcr.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3382-2441</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Балмасов</surname><given-names>Е. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Balmasov</surname><given-names>E. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Российская Федерация, 111123, Москва, ул. Н овогиреевская, 3а</p></bio><bio xml:lang="en"><p>3a, Novogireevskaya St., Moscow, 111123, Russian Federation</p></bio><email xlink:type="simple">crie@pcr.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6743-3650</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мосунов</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Mosunov</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Российская Федерация, 111123, Москва, ул. Н овогиреевская, 3а</p></bio><bio xml:lang="en"><p>3a, Novogireevskaya St., Moscow, 111123, Russian Federation</p></bio><email xlink:type="simple">crie@pcr.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФБУН «Центральный научно-исследовательский институт эпидемиологии»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Central Research Institute of Epidemiology</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБУ «Национальный исследовательский центр эпидемиологии и микробиологии им. Н.Ф. Гамалеи»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>N.F. Gamaley National Research Center of Epidemiology and Microbiology</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>18</day><month>10</month><year>2020</year></pub-date><volume>0</volume><issue>3</issue><fpage>27</fpage><lpage>35</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Акимкин В.Г., Кузин С.Н., Семененко Т.А., Плоскирева А.А., Дубоделов Д.В., Тиванова Е.В., Пшеничная Н.Ю., Каленская А.В., Яцышина С.Б., Шипулина О.Ю., Родионова Е.Н., Петрова Н.С., Соловьева И.В., Квасова О.А., Вершинина М.А., Мамошина М.В., Клушкина В.В., Чурилова Н.С., Панасюк Я.В., Власенко Н.В., Остроушко А.А., Балмасов Е.С., Мосунов А.В., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Акимкин В.Г., Кузин С.Н., Семененко Т.А., Плоскирева А.А., Дубоделов Д.В., Тиванова Е.В., Пшеничная Н.Ю., Каленская А.В., Яцышина С.Б., Шипулина О.Ю., Родионова Е.Н., Петрова Н.С., Соловьева И.В., Квасова О.А., Вершинина М.А., Мамошина М.В., Клушкина В.В., Чурилова Н.С., Панасюк Я.В., Власенко Н.В., Остроушко А.А., Балмасов Е.С., Мосунов А.В.</copyright-holder><copyright-holder xml:lang="en">Akimkin V.G., Kuzin S.N., Semenenko T.A., Ploskireva A.A., Dubodelov D.V., Tivanova E.V., Pshenichnaya N.Y., Kalenskaya A.V., Yatsyshina S.B., Shipulina O.Y., Rodionova E.N., Petrova N.S., Solov’eva I.V., Kvasova O.A., Vershinina M.A., Mamoshina M.V., Klushkina V.V., Churilova N.S., Panasyuk Y.V., Vlasenko N.V., Ostroushko A.A., Balmasov E.S., Mosunov A.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.microbe.ru/jour/article/view/1360">https://journal.microbe.ru/jour/article/view/1360</self-uri><abstract><p>Продолжающаяся пандемия COVID-19 в мире и в России остается главным событием 2020 г. Во всем мире проводятся исследования по всестороннему изучению закономерностей и проявлений эпидемического процесса COVID-19. Для разработки системы эпидемиологического надзора важное значение имеют основные количественные характеристики динамики распространения SARS-CoV-2 в популяции, основанные на материалах официального мониторинга за текущей ситуацией.</p><p>Цель исследования – изучение особенностей гендерно-возрастной структуры пациентов с COVID-19 в Москве.</p><sec><title>Материалы и методы</title><p>Материалы и методы. Проведен ретроспективный эпидемиологический анализ данных по изучению гендерно-возрастной структуры заболевших COVID-19 в период с 6 марта по 6 июля 2020 г. в различные фазы развития эпидемии в Москве. </p></sec><sec><title>Результаты и обсуждение</title><p>Результаты и обсуждение. Средний возраст заболевших COVID-19 в Москве за изучаемый период составил (46,41±20,58) года. Гендерная пропорция среди заболевших COVID-19 в Москве составляла 52,7/47,3 %, при этом показатели варьировали в зависимости от возраста. Соотношение мужчины/женщины в возрастной группе «до 39 лет» составляло 53,7/46,3 %, а у пациентов старше 40 лет – 39,3/60,7 %. В группе мужчин, заболевших COVID-19, превалировали пациенты в возрасте 19–39 лет (35,4 %), тогда как среди женщин – больные в возрасте 40–59 лет (36,5 %). Возрастная структура пациентов в Москве указывает на то, что COVID-19 является заболеванием, в первую очередь, лиц старших возрастных групп. Возрастная структура всех заболевших COVID-19 за период наблюдения характеризуется преобладанием взрослых пациентов старше 19 лет – 92,7 % (92,6–92,8 %), в том числе доля пациентов в возрасте 40–59 лет составляет 35,7 % (35,5–35,9 %). Показаны различия в возрастной структуре мужчин и женщин с COVID-19: среди мужчин наиболее высокий удельный вес у пациентов двух возрастных групп: «19–39 лет» и «40–59 лет» – 35,4 % (35,1–35,7 %) и 34,9 % (34,6–35,2 %), среди женщин превалировали пациентки 40–59 лет – 36,5 % (36,3–36,8 %). </p></sec></abstract><trans-abstract xml:lang="en"><p>The ongoing COVID-19 pandemic around the world and in Russia remains a major event of 2020. All over the world, research is being conducted to comprehensively study the patterns and manifestations of the epidemic  process. The main quantitative characteristics of SARS-CoV-2 transmission dynamics among the population, based on the data of official monitoring over the current situation, play an important role in the development of  the epidemiological surveillance system.</p><p>The aim of this study is to explore the peculiarities of age-gender distribution of COVID-19 patients in Moscow.</p><sec><title>Material and methods</title><p>Material and methods. The data related to the epidemiological characteristics of age-gender structure of COVID-19 patients in Moscow between March 19, 2020 and April 15, 2020, at different stages of the  epidemic were retrospectively analyzed.</p></sec><sec><title>Results and discussion</title><p>Results and discussion. The mean age of COVID-19 patients in Moscow was 46,41±20,58 years. The gender ratio (male/female) among the patients was 52.7/47.3 %, wherein the indicators varied depending upon the  age. Male/female ratio in the age group “under 39” stood at 53.7/46.3 %, and “over 40 years of age” – at  39.3/60.7 %. The predominant age range among male cases was 19 to 39 years old – 35.4 %, while among female patients – 40–59 years (36.5 %). The age distribution of patients in Moscow is indicative of the fact that COVID-19 is a disease that primarily affects older age groups. The age structure of all COVID-19 cases during the observation period is characterized by predominance of adult patients over 19 years of age – 92,7 % (92,6–92,8 %), the share of patients aged 40–59 years is 35,7% (35,5–35,9 %). The differences in the age distribution in males and females are as follows: in the male cohort, the age groups 19–39 years old and 40–59 years old prevail – 35.4 % (35.1–35.7 %) and 34.9 % (34.6–35.2 %), respectively. The age group 40–59 years old – 36.5 % (36.3–36.8%) dominates in the female cohort. </p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>COVID-19</kwd><kwd>гендерно-возрастная структура</kwd><kwd>эпидемический процесс</kwd><kwd>система эпидемиологического надзора</kwd><kwd>SARS-CoV-2</kwd></kwd-group><kwd-group xml:lang="en"><kwd>COVID-19</kwd><kwd>age-gender distribution</kwd><kwd>epidemic process</kwd><kwd>epidemiological surveillance system</kwd><kwd>SARS-CoV-2</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Lechien J.R., Chiesa-Estomba C.M., Place S., Laethem Y.V., Cabaraux P., Mat Q., Huet K., Plzak J., Horoi M., Hans S., Barillari M.R., Cammaroto G., Fakhry N., Martiny D., Ayad T., Jouffe L., Hopkins C., Saussez S. Clinical and epidemiological characteristics of 1420 European patients with mild-to-moderate coronavirus disease 2019. J. Intern. 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