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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">microbe</journal-id><journal-title-group><journal-title xml:lang="ru">Проблемы особо опасных инфекций</journal-title><trans-title-group xml:lang="en"><trans-title>Problems of Particularly Dangerous Infections</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0370-1069</issn><issn pub-type="epub">2658-719X</issn><publisher><publisher-name>Russian Research Anti-Plague Institute “Microbe”</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21055/0370-1069-2020-3-154-157</article-id><article-id custom-type="elpub" pub-id-type="custom">microbe-1378</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КРАТКИЕ СООБЩЕНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>BRIEF COMMUNICATIONS</subject></subj-group></article-categories><title-group><article-title>Нарушения функции желудочно-кишечного тракта при COVID-19 у детей</article-title><trans-title-group xml:lang="en"><trans-title>Gastrointestinal Tract Disorders in COVID-19 Infected Children</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Попова</surname><given-names>Р. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Popova</surname><given-names>R. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Российская Федерация, 111123, Москва, ул. Новогиреевская, 3а</p><p>Российская Федерация, Мытищи</p></bio><bio xml:lang="en"><p>3a, Novogireevskaya St., Moscow, 111123, Russian Federation</p><p>Mytishchi, Russian Federation</p></bio><email xlink:type="simple">crie@pcr.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6945-2019</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Руженцова</surname><given-names>Т. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Ruzhentsova</surname><given-names>T. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Российская Федерация, 111123, Москва, ул. Новогиреевская, 3а</p></bio><bio xml:lang="en"><p>3a, Novogireevskaya St., Moscow, 111123, Russian Federation</p></bio><email xlink:type="simple">ruzhencova@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5919-9841</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хавкина</surname><given-names>Д. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Khavkina</surname><given-names>D. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Российская Федерация, 111123, Москва, ул. Новогиреевская, 3а</p></bio><bio xml:lang="en"><p>3a, Novogireevskaya St., Moscow, 111123, Russian Federation</p></bio><email xlink:type="simple">crie@pcr.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1210-1215</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чухляев</surname><given-names>П. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Chukhlyaev</surname><given-names>P. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Российская Федерация, 111123, Москва, ул. Новогиреевская, 3а</p></bio><bio xml:lang="en"><p>3a, Novogireevskaya St., Moscow, 111123, Russian Federation</p></bio><email xlink:type="simple">crie@pcr.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3378-8418</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гарбузов</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Garbuzov</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Российская Федерация, 111123, Москва, ул. Новогиреевская, 3а</p></bio><bio xml:lang="en"><p>3a, Novogireevskaya St., Moscow, 111123, Russian Federation</p></bio><email xlink:type="simple">crie@pcr.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мешкова</surname><given-names>Н. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Meshkova</surname><given-names>N. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Российская Федерация, 119435, Москва, ул. Большая Пироговская, д. 2, стр. 4</p></bio><bio xml:lang="en"><p>2, building 4, Bolshaya Pirogovskaya St., Moscow, 119435, Russian Federation</p></bio><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФБУН «Центральный научно-исследовательский институт эпидемиологии»;&#13;
ГБУЗ МО «Мытищинская городская клиническая больница»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Central Research Institute of Epidemiology;&#13;
Mytishchi State Clinical Hospital</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФБУН «Центральный научно-исследовательский институт эпидемиологии»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Central Research Institute of Epidemiology</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ФГАОУ ВО «Первый Московский государственный медицинский университет имени И.М. Сеченова»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>First Moscow State Medical University n.a. I.M. Sechenov</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>22</day><month>10</month><year>2020</year></pub-date><volume>0</volume><issue>3</issue><fpage>154</fpage><lpage>157</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Попова Р.В., Руженцова Т.А., Хавкина Д.А., Чухляев П.В., Гарбузов А.А., Мешкова Н.А., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Попова Р.В., Руженцова Т.А., Хавкина Д.А., Чухляев П.В., Гарбузов А.А., Мешкова Н.А.</copyright-holder><copyright-holder xml:lang="en">Popova R.V., Ruzhentsova T.A., Khavkina D.A., Chukhlyaev P.V., Garbuzov A.A., Meshkova N.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.microbe.ru/jour/article/view/1378">https://journal.microbe.ru/jour/article/view/1378</self-uri><abstract><p>Цель исследования – изучить особенности нарушений функции желудочно-кишечного тракта у детей, больных коронавирусной инфекцией, вызванной вирусом SARS-CoV-2.</p><sec><title>Материалы и методы</title><p>Материалы и методы. Проанализирована частота, сроки появления, продолжительность и характер желудочно-кишечных нарушений по данным историй болезней 36 детей, находившихся на лечении с диагнозом «внебольничная  пневмония коронавирусной этиологии (вирус SARS-CoV-2 идентифицирован)» в детском инфекционном отделении ГБУЗ  МО «МГКБ » г. Мытищи.</p></sec><sec><title>Результаты и обсуждение</title><p>Результаты и обсуждение. Желудочно-кишечные нарушения у 23 детей (64 %) проявлялись на 4–5-й день, у 8 (22 %) – до начала терапии, продолжались от 3 до 5 дней. У большинства детей отмечали диарею (64 %) и боли в животе (57 %). Другие симптомы, свидетельствующие о дисфункции желудочно-кишечного тракта, зарегистрированы у 67 % детей. Желудочно-кишечные нарушения имеются у большинства детей,  госпитализированных с внебольничной пневмонией, вызванной вирусом SARS-CoV-2.  Симптоматика купируется при проведении курса основной терапии, показанной для лечения COVID-19, и дополнительной, рекомендуемой при острых кишечных инфекциях.</p></sec></abstract><trans-abstract xml:lang="en"><p>Objective of the work was to investigate the peculiarities of gastrointestinal tract disorders in children with coronavirus disease caused by SARS-CoV-2 virus.</p><sec><title>Materials and methods</title><p>Materials and methods. We have analyzed the frequency, terms of emergence, duration and character of gastrointestinal disorders on the basis of medical records of 36 children receiving the treatment for community-acquired pneumonia of coronavirus etiology (positive for SARS-CoV-2 virus) in the children’s infectious disease department of Moscow State Clinical Hospital, Mytishchi. The majority of patients had moderate form of the disease (97 %), severe cases were not registered. The age range of the children – 8 months to17 years old. All patients were subjected to supplementary examination on Day 1 in accordance with the current recommendations. Children were treated in hospital settings for 8–15 days. Assessment of clinical status was performed at least once a day over the stated period, supplementary survey – at least once in a week, upon indications – more frequently. SARSCoV-2 virus was identified using polymerase chain reaction. All patients received standard therapy in compliance with advanced methodological recommendations, upon indications – other pharmaceutical products.</p></sec><sec><title>Results and discussion</title><p>Results and discussion. Gastro-intestinal disorders in 23 children (64 %) emerged on Day 4–5, in 8 children (22 %) – before the start of the treatment; they lasted 3–5 days. In most of the patients diarrhea (64 %) and stomachaches (57 %) were observed. 67 % of the children demonstrated other symptoms indicative of gastrointestinal dysfunction. The disorders were characteristic for most of the children hospitalized with community-acquired pneumonia caused by SARS-CoV-2 virus. The symptoms are contained when the main course of therapy is conducted, indicated for treatment of COVID-19, and additional therapy recommended for management of gastro-intestinal infections is performed. </p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>абдоминальная боль</kwd><kwd>дети</kwd><kwd>диарея</kwd><kwd>коронавирус</kwd><kwd>пневмония</kwd><kwd>COVID-19</kwd><kwd>SARS-CoV-2</kwd></kwd-group><kwd-group xml:lang="en"><kwd>abdominal pain</kwd><kwd>children</kwd><kwd>diarrhea</kwd><kwd>coronavirus</kwd><kwd>pneumonia</kwd><kwd>COVID-19</kwd><kwd>SARS-CoV-2</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Tang X., Wu C., Li X., Yu-He Song, Xinmin Yao, Xinkai Wu, Yuange Duan, Zhang H., Yirong Wang, Zhaohui Qian, Jie Cui, Lu J. On the origin and continuing evolution of SARS-CoV-2. National Science Review. 2020; 7(6):1012–23. 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