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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">microbe</journal-id><journal-title-group><journal-title xml:lang="ru">Проблемы особо опасных инфекций</journal-title><trans-title-group xml:lang="en"><trans-title>Problems of Particularly Dangerous Infections</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0370-1069</issn><issn pub-type="epub">2658-719X</issn><publisher><publisher-name>Russian Research Anti-Plague Institute “Microbe”</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21055/0370-1069-2013-1-70-73</article-id><article-id custom-type="elpub" pub-id-type="custom">microbe-14</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>МИКРОБИОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>MICROBIOLOGY</subject></subj-group></article-categories><title-group><article-title>Создание базы данных по характеристикам нуклеотидных последовательностей геномов штаммов возбудителей бактериальных и вирусных инфекций I–II групп патогенности</article-title><trans-title-group xml:lang="en"><trans-title>Setting-up of the Database on the Nucleotide Sequences of the Genomes of the Strains of Bacterial and Viral Infections Agents of the I–II Pathogenicity Groups</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Яшечкин</surname><given-names>Ю. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Yashechkin</surname><given-names>Yu. I.</given-names></name></name-alternatives><email xlink:type="simple">rusrapi@microbe.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Найденова</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Naydenova</surname><given-names>E. V.</given-names></name></name-alternatives><email xlink:type="simple">rusrapi@microbe.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бугоркова</surname><given-names>Т. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Bugorkova</surname><given-names>T. V.</given-names></name></name-alternatives><email xlink:type="simple">rusrapi@microbe.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Щербакова</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Shcherbakova</surname><given-names>S. A.</given-names></name></name-alternatives><email xlink:type="simple">rusrapi@microbe.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Российский научно-исследовательский противочумный институт «Микроб»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian Research Anti-Plague Institute “Microbe”</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2013</year></pub-date><pub-date pub-type="epub"><day>20</day><month>03</month><year>2013</year></pub-date><volume>0</volume><issue>1</issue><fpage>70</fpage><lpage>73</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Яшечкин Ю.И., Найденова Е.В., Бугоркова Т.В., Щербакова С.А., 2013</copyright-statement><copyright-year>2013</copyright-year><copyright-holder xml:lang="ru">Яшечкин Ю.И., Найденова Е.В., Бугоркова Т.В., Щербакова С.А.</copyright-holder><copyright-holder xml:lang="en">Yashechkin Y.I., Naydenova E.V., Bugorkova T.V., Shcherbakova S.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.microbe.ru/jour/article/view/14">https://journal.microbe.ru/jour/article/view/14</self-uri><abstract><p>Разработана база данных (БД), содержащая характеристики вариабельных тандемных повторов, олигонуклеотидных праймеров и зондов геномов штаммов возбудителей бактериальных и вирусных инфекций I–II групп патогенности. БД позволяет накапливать информацию об участках геномов, а с использованием встроенных VB-приложений быстро проводить анализ данных и осуществлять информативно обоснованный расчет генодиагностических препаратов, основанных на различных форматах полимеразной цепной реакции.</p></abstract><trans-abstract xml:lang="en"><p>Set-up is database containing characteristics of variable tandem repeats, oligo-nucleotide primers and probes of the genomes of the strains bacterial and viral infections agents of the I-II pathogenicity groups. It allows for accumulation of information on genome regions. Using the incorporated VBA one can rapidly analyze the data and carry out substantiated calculation of gene-diagnostic preparations based on various PCR frameworks.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>база данных</kwd><kwd>ПЦР</kwd><kwd>VNTR</kwd><kwd>генодиагностические препараты</kwd><kwd>database</kwd><kwd>PCR</kwd><kwd>gene-diagnostic preparations</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Красовская Т.Ю., Шарова И.Н., Щербакова С.А., Яшечкин Ю.И., Хуторецкая Н.В., Ларичев В.Ф., Бутенко А.М., Куличенко А.Н. Разработка и внедрение тест-системы для лабораторной диагностики лихорадки Западного Нила методом ПЦР. ЗНиСО. 2007; 6(171):42–6.</mixed-citation><mixed-citation xml:lang="en">Krasovskaya T.Yu., Sharova I.N., Shcherbakova S.A., Yashechkin Yu.I., Khutoretskaya N.V., Larichev V.F., Butenko A.M., Kulichenko A.N. 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