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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">microbe</journal-id><journal-title-group><journal-title xml:lang="ru">Проблемы особо опасных инфекций</journal-title><trans-title-group xml:lang="en"><trans-title>Problems of Particularly Dangerous Infections</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0370-1069</issn><issn pub-type="epub">2658-719X</issn><publisher><publisher-name>Russian Research Anti-Plague Institute “Microbe”</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21055/0370-1069-2020-4-34-40</article-id><article-id custom-type="elpub" pub-id-type="custom">microbe-1401</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>Эпидемиологическая ситуация по COVID-19 в Иркутской области и прогноз ее распространения</article-title><trans-title-group xml:lang="en"><trans-title>Epidemiological Situation on COVID-19 in Irkutsk Region and Forecast for its Spread</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4201-5828</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Балахонов</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Balakhonov</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>664047, Иркутск, ул. Трилиссера, 78</p></bio><bio xml:lang="en"><p>78, Trilissera St., Irkutsk, 664047</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5489-9363</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чеснокова</surname><given-names>М. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Chesnokova</surname><given-names>M. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>664047, Иркутск, ул. Трилиссера, 78</p></bio><bio xml:lang="en"><p>78, Trilissera St., Irkutsk, 664047</p></bio><email xlink:type="simple">adm@chumin.irkutsk.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5678-468X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пережогин</surname><given-names>А. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Perezhogin</surname><given-names>A. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>664047, Иркутск, ул. Трилиссера, 78</p></bio><bio xml:lang="en"><p>78, Trilissera St., Irkutsk, 664047</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3918-7832</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Никитин</surname><given-names>А. Я.</given-names></name><name name-style="western" xml:lang="en"><surname>Nikitin</surname><given-names>A. Ya.</given-names></name></name-alternatives><bio xml:lang="ru"><p>664047, Иркутск, ул. Трилиссера, 78</p></bio><bio xml:lang="en"><p>78, Trilissera St., Irkutsk, 664047</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Каверзина</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kaverzina</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>664047, Иркутск, ул. Трилиссера, 78</p></bio><bio xml:lang="en"><p>78, Trilissera St., Irkutsk, 664047</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9207-7536</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бренева</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Breneva</surname><given-names>N. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>664047, Иркутск, ул. Трилиссера, 78</p></bio><bio xml:lang="en"><p>78, Trilissera St., Irkutsk, 664047</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5315-4797</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дугаржапова</surname><given-names>З. Ф.</given-names></name><name name-style="western" xml:lang="en"><surname>Dugarzhapova</surname><given-names>Z. F.</given-names></name></name-alternatives><bio xml:lang="ru"><p>664047, Иркутск, ул. Трилиссера, 78</p></bio><bio xml:lang="en"><p>78, Trilissera St., Irkutsk, 664047</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Савиных</surname><given-names>Д. Ф.</given-names></name><name name-style="western" xml:lang="en"><surname>Savinykh</surname><given-names>D. F.</given-names></name></name-alternatives><bio xml:lang="ru"><p>664003, Иркутск, ул. Карла Маркса, 8</p></bio><bio xml:lang="en"><p>8, Karl Marks St., Irkutsk, 664003</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Поталицина</surname><given-names>Н. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Potalitsina</surname><given-names>N. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>664003, Иркутск, ул. Карла Маркса, 8</p></bio><bio xml:lang="en"><p>8, Karl Marks St., Irkutsk, 664003</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гаврилова</surname><given-names>Т. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Gavrilova</surname><given-names>T. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>664003, Иркутск, ул. Карла Маркса, 8</p></bio><bio xml:lang="en"><p>8, Karl Marks St., Irkutsk, 664003</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лиханова</surname><given-names>Н. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Likhanova</surname><given-names>N. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>664003, Иркутск, ул. Карла Маркса, 8</p></bio><bio xml:lang="en"><p>8, Karl Marks St., Irkutsk, 664003</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чумаченко</surname><given-names>И. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Chumachenko</surname><given-names>I. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>664003, Иркутск, ул. Карла Маркса, 8</p></bio><bio xml:lang="en"><p>8, Karl Marks St., Irkutsk, 664003</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хакимова</surname><given-names>М. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Khakimova</surname><given-names>M. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>664047, Иркутск, ул. Трилиссера, 51</p></bio><bio xml:lang="en"><p>51, Trilissera St., Irkutsk, 664047</p></bio><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФКУЗ «Иркутский научно-исследовательский противочумный институт Сибири и Дальнего Востока</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Irkutsk Research Anti-Plague Institute of Siberia and Far East</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Управление Роспотребнадзора по Иркутской области</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Rospotrebnadzor Administration in the Irkutsk Region</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ФБУЗ «Центр гигиены и эпидемиологии в Иркутской области»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Center of Hygiene and Epidemiology in the Irkutsk Region</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>04</day><month>02</month><year>2021</year></pub-date><volume>0</volume><issue>4</issue><fpage>34</fpage><lpage>40</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Балахонов С.В., Чеснокова М.В., Пережогин А.Н., Никитин А.Я., Каверзина С.В., Бренева Н.В., Дугаржапова З.Ф., Савиных Д.Ф., Поталицина Н.Е., Гаврилова Т.А., Лиханова Н.А., Чумаченко И.Г., Хакимова М.И., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Балахонов С.В., Чеснокова М.В., Пережогин А.Н., Никитин А.Я., Каверзина С.В., Бренева Н.В., Дугаржапова З.Ф., Савиных Д.Ф., Поталицина Н.Е., Гаврилова Т.А., Лиханова Н.А., Чумаченко И.Г., Хакимова М.И.</copyright-holder><copyright-holder xml:lang="en">Balakhonov S.V., Chesnokova M.V., Perezhogin A.N., Nikitin A.Y., Kaverzina S.V., Breneva N.V., Dugarzhapova Z.F., Savinykh D.F., Potalitsina N.E., Gavrilova T.A., Likhanova N.A., Chumachenko I.G., Khakimova M.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.microbe.ru/jour/article/view/1401">https://journal.microbe.ru/jour/article/view/1401</self-uri><abstract><p>Широкое распространение новой коронавирусной инфекции COVID-19 в Российской Федерации определяет актуальность оценки конкретной территории по ее эпидемиологической значимости.</p><p>Цель исследования – выявление эпидемиологических особенностей и установление тенденций эпидемического процесса новой коронавирусной инфекции COVID-19 в Иркутской области и прогнозирование ее распространения.</p><sec><title>Материалы и методы</title><p>Материалы и методы. Проведен оперативный анализ эпидемиологической ситуации по COVID-19 в Иркутской области по состоянию на 16.08.2020, обоснованы ограничительные мероприятия на основании расчета коэффициента распространения инфекции (Rt).</p></sec><sec><title>Результаты и обсуждение</title><p>Результаты и обсуждение. Иркутская область по заболеваемости людей COVID-19 на 16.08.2020 продолжает оставаться одной из неблагополучных территорий в Сибирском федеральном округе и Российской Федерации. Определена постепенная динамика развития эпидемического процесса, которой на первом этапе эпидемии способствовали завозные случаи из неблагополучных стран и регионов Российской Федерации, а в последующем – местная передача. Подъем заболеваемости зафиксирован на два месяца позже по сравнению с центральными регионами РФ, в настоящее время наметилась устойчивая тенденция к снижению заболеваемости. Рост случаев инфицирования превалировал среди лиц, прибывающих на вахтовые и сезонные работы в административный центр и северные районы Иркутской области. Определен характер эпидемического процесса по гендерному, возрастному и социальному проявлениям. Показано, что риск заболеваемости новой коронавирусной инфекцией определяется интенсивностью контакта в семейных очагах, распространением в медицинских организациях и значительной долей бессимптомного носительства. Установлены высокие показатели летальности (0,7 %) и смертности (31,1 ⁰/₀₀₀₀) среди лиц старше 65 лет. Наблюдаемый с июня стационарный временной ряд изменения Rt-показателя с колебаниями от 0,92 до 1,01 требует сохранения контроля проводимых ограничительных мероприятий с оперативным принятием управленческих решений, исходя из складывающейся эпидемиологической ситуации в Иркутской области и с учетом оценки рисков ее возможного осложнения.</p></sec></abstract><trans-abstract xml:lang="en"><p>Assessment of a particular territory by its epidemiological significance is very relevant in the light of widespread occurrence of new coronavirus infection, COVID-19, in the Russian Federation.</p><sec><title>Objective</title><p>Objective. Detection of the epidemiological features and revealing trends in the epidemic process of new coronavirus infection in the Irkutsk Region and forecasting of its spread.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. An operational analysis of the epidemiological situation on COVID-19 in the Irkutsk Region as of August 16, 2020 was performed. Restrictive measures were substantiated based on the calculation of the infection spread rate (Rt).</p></sec><sec><title>Results and discussion</title><p>Results and discussion. Irkutsk Region remained one of the adverse territories as regards human COVID-19 incidence in the Siberian Federal District and the Russian Federation as of August 16, 2020. The gradual dynamics of the epidemic process was revealed: at the first stage of the epidemic development it was facilitated by the imported cases from affected countries and regions of the Russian Federation, and subsequently by local transmission. The incidence increase was registered 2 months later than in central regions of the Russian Federation. Currently there is a consistent downward trend. The increase in the cases prevailed among rotation workers staying for shift and seasonal activities in the administrative center and northern districts of the Irkutsk Region. The epidemic pattern was determined by gender, age and social characteristics. It is demonstrated that the risk of the new coronavirus infection is determined by the intensity of contacts in family foci, the spread of infection in medical organizations and a significant proportion of asymptomatic carriers. High lethality rates (0.7 %) and mortality rates (31.1 o / oooo) were established among persons over 65 years. The stationary time series observed since June for changing the Rt-indicator with fluctuations ranging from 0.92 to 1.01 requires maintaining control of restrictive measures with prompt management decisions making based on the evolving epidemiological situation in the Irkutsk Region and taking into account the assessment of its possible complication risks. </p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>COVID-19</kwd><kwd>заболеваемость</kwd><kwd>эпидемиологическая ситуация</kwd><kwd>прогноз</kwd></kwd-group><kwd-group xml:lang="en"><kwd>COVID-19</kwd><kwd>incidence</kwd><kwd>epidemiological situation</kwd><kwd>forecast</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Кутырев В.В., Попова А.Ю., Смоленский В.Ю., Ежлова Е.Б., Демина Ю.В., Сафронов В.А., Карнаухов И.Г., Иванова А.В., Щербакова С.А. 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