microbeПроблемы особо опасных инфекцийProblems of Particularly Dangerous Infections0370-10692658-719XRussian Research Anti-Plague Institute “Microbe”10.21055/0370-1069-2014-2-80-84microbe-144Research ArticleМИКРОБИОЛОГИЯMICROBIOLOGYОсобенности циркуляции вируса венесуэльского энцефаломиелита лошадей (обзор)Peculiarities of Circulation of Venezuelan Equine Encephalomyelitis Virus (Scientific Review)ПетровА. А.PetrovA. A.noemail@neicon.ruЛебедевВ. Н.LebedevV. N.noemail@neicon.ruРучкоВ. М.RuchkoV. M.noemail@neicon.ruКарулинаН. В.KarulinaN. V.noemail@neicon.ruБорисевичС. В.BorisevichS. V.noemail@neicon.ru48 Центральный научно-исследовательский институт Министерства обороны Российской ФедерацииРоссияThe 48th Central Research Institute of the RF Ministry of DefenseRussian Federation201420062014028084Copyright © Петров А.А., Лебедев В.Н., Ручко В.М., Карулина Н.В., Борисевич С.В., 20142014Петров А.А., Лебедев В.Н., Ручко В.М., Карулина Н.В., Борисевич С.В.Petrov A.A., Lebedev V.N., Ruchko V.M., Karulina N.V., Borisevich S.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.microbe.ru/jour/article/view/144

В обзоре рассмотрены некоторые особенности циркуляции вируса венесуэльского энцефаломиелита лошадей (ВЭЛ). Энзоотические штаммы вируса ВЭЛ в настоящее время играют все возрастающую роль как этиологические агенты заболеваний у людей. Большинство случаев ВЭЛ у людей в эндемичных регионах в межэпидемический период вызваны инфицированием вирусом ВЭЛ подтипа ID, который включает в себя 6 генотипов. От людей выделены генотипы Колумбия/Венесуэла, Панама/Перу и Перу/Боливия подтипа ID вируса ВЭЛ. Возможность возникновения новых эпидемических вспышек ВЭЛ обусловлена мутациями штамма ID подтипа в IС подтип, который и представляет в настоящее время потенциальную угрозу как этиологический агент заболевания.

Reviewed are some peculiarities of circulation of Venezuelan equine encephalomyelitis virus (VEE), the enzootic strains of which play an increasingly important part as etiological agents of human infections nowadays. The majority of VEE cases among the residents of the endemic regions within the inter-epidemic period are caused by the ID subtype of VEE that includes 6 genotypes. Isolated from humans have been the genotypes Columbia/Venezuela, Panama/Peru, and Peru/Bolivia, ID subtype of VEE. Possibility of emergence of new VEE outbreaks is associated with ID subtype mutation into the IC subtype, which is assumed to be a potential threat as etiological agent of the disease at present.

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The authors declare that there are no conflicts of interest present.