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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">microbe</journal-id><journal-title-group><journal-title xml:lang="ru">Проблемы особо опасных инфекций</journal-title><trans-title-group xml:lang="en"><trans-title>Problems of Particularly Dangerous Infections</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0370-1069</issn><issn pub-type="epub">2658-719X</issn><publisher><publisher-name>Russian Research Anti-Plague Institute “Microbe”</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21055/0370-1069-2021-1-134-139</article-id><article-id custom-type="elpub" pub-id-type="custom">microbe-1449</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>Лептоспироз в Республике Татарстан. Эпидемиологические особенности</article-title><trans-title-group xml:lang="en"><trans-title>Leptospirosis in the Republic of Tatarstan. Epidemiological Features</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9103-303X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Савицкая</surname><given-names>Т. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Savitskaya</surname><given-names>T. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>420015, Казань, ул. Большая Красная, 67</p></bio><bio xml:lang="en"><p>67, Bolshaya Krasnaya St., 420015, Kazan</p></bio><email xlink:type="simple">kniem@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8374-6024</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Трифонов</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Trifonov</surname><given-names>V. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>420015, Казань, ул. Большая Красная, 67; 420015, Казань, ул. Бутлерова, 36</p></bio><bio xml:lang="en"><p>67, Bolshaya Krasnaya St., 420015, Kazan; 36, Butlerova St., 420015, Kazan</p></bio><email xlink:type="simple">kniem@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0181-6864</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Милова</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Milova</surname><given-names>I. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>420061, Казань, ул. Сеченова, 13а</p></bio><bio xml:lang="en"><p>13a Sechenova St., 420061, Kazan</p></bio><email xlink:type="simple">fguz.ooi@tatar.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9719-9583</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Исаева</surname><given-names>Г. Ш.</given-names></name><name name-style="western" xml:lang="en"><surname>Isaeva</surname><given-names>G. Sh.</given-names></name></name-alternatives><bio xml:lang="ru"><p>420015, Казань, ул. Большая Красная, 67</p></bio><bio xml:lang="en"><p>67, Bolshaya Krasnaya St., 420015, Kazan</p></bio><email xlink:type="simple">kniem@mail.ru</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2600-7414</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Решетникова</surname><given-names>И. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Reshetnikova</surname><given-names>I. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>420015, Казань, ул. Большая Красная, 67</p></bio><bio xml:lang="en"><p>67, Bolshaya Krasnaya St., 420015, Kazan</p></bio><email xlink:type="simple">kniem@mail.ru</email><xref ref-type="aff" rid="aff-5"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7178-9609</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Серова</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Serovа</surname><given-names>I. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>420015, Казань, ул. Большая Красная, 67</p></bio><bio xml:lang="en"><p>67, Bolshaya Krasnaya St., 420015, Kazan</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФБУН «Казанский научно-исследовательский институт эпидемиологии и микробиологии»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Kazan Research Institute of Epidemiology and Microbiology</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФБУН «Казанский научно-исследовательский институт эпидемиологии и микробиологии»;&#13;
Казанская государственная медицинская академия – филиал ФГБОУ ДПО РМАНПО Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Kazan Research Institute of Epidemiology and Microbiology;&#13;
Kazan State Medical Academy</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ФБУЗ «Центр гигиены и эпидемиологии в Республике Татарстан (Татарстан)»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Center for Hygiene and Epidemiology in the Republic of Tatarstan</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>ФБУН «Казанский научно-исследовательский институт эпидемиологии и микробиологии»;&#13;
ФГБОУ ВО «Казанский государственный медицинский университет»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Kazan Research Institute of Epidemiology and Microbiology;&#13;
Kazan State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-5"><aff xml:lang="ru"><institution>ФБУН «Казанский научно-исследовательский институт эпидемиологии и микробиологии»;&#13;
ФГАОУ ВО «Казанский (Приволжский) федеральный университет»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Kazan Research Institute of Epidemiology and Microbiology;&#13;
Kazan (Privolzhsky) Federal University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>16</day><month>04</month><year>2021</year></pub-date><volume>0</volume><issue>1</issue><fpage>134</fpage><lpage>139</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Савицкая Т.А., Трифонов В.А., Милова И.В., Исаева Г.Ш., Решетникова И.Д., Серова И.В., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Савицкая Т.А., Трифонов В.А., Милова И.В., Исаева Г.Ш., Решетникова И.Д., Серова И.В.</copyright-holder><copyright-holder xml:lang="en">Savitskaya T.A., Trifonov V.A., Milova I.V., Isaeva G.S., Reshetnikova I.D., Serovа I.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.microbe.ru/jour/article/view/1449">https://journal.microbe.ru/jour/article/view/1449</self-uri><abstract><p>Целью исследования является характеристика современной эпидемиологической ситуации по лептоспирозу в Республике Татарстан, изучение циркуляции возбудителей лептоспироза в популяции мелких млекопитающих и видового состава лептоспир, вызвавших заболевания у людей.</p><sec><title>Материалы и методы</title><p>Материалы и методы. В работе использованы данные по заболеваемости населения лептоспирозом на территории Российской Федерации (РФ) за период с 2000 по 2018 год, на территории Республики Татарстан – с 1998 г., представленные управлениями Роспотребнадзора по субъектам РФ, материалы ФБУЗ «Центр гигиены и эпидемиологии в Республике Татарстан (Татарстан)» и Главного управления ветеринарии Республики Татарстан.</p></sec><sec><title>Результаты и обсуждение</title><p>Результаты и обсуждение. Проведен анализ эпидемиологической ситуации в Республике Татарстан за период 1998–2018 гг. по административным территориям республики. Проанализирована заболеваемость лептоспирозом людей, вызванная различными серогруппами лептоспир. Всего за анализируемый период заболело лептоспирозом 112 человек. Приведены данные исследования мелких млекопитающих, обитающих в природных очагах лептоспироза на территории республики. Проведены лабораторные исследования 1565 проб от мышевидных грызунов на зараженность возбудителями лептоспироза, из них 1,9 % дали положительный результат. Доминирующими в Республике Татарстан являются серогруппы лептоспир Leptospira grippotyphosa и L. hebdomadis. Результаты лабораторных исследований на носительство лептоспир среди мелких млекопитающих и инфицированность ими объектов окружающей среды свидетельствуют о циркуляции возбудителей лептоспироза в популяции мелких млекопитающих, обитающих в лесокустарниковых, околоводных и луго-полевых стациях республики. Преобладает в данном сообществе рыжая полевка, средний индекс ее доминирования составляет 66,7 %. Данные эпизоотологического мониторинга указывают на скрыто протекающий эпизоотический процесс в сообществе мышевидных грызунов.</p></sec></abstract><trans-abstract xml:lang="en"><p>The study presents a characteristic of the current epidemiological situation on leptospirosis in the Republic of Tatarstan, investigation of the circulation of leptospirosis agents among the population of small mammals, and the species composition of Leptospira that caused diseases in humans.</p><sec><title>Materials and methods</title><p>Materials and methods. The paper contains the data on the incidence of leptospirosis among the population in the Russian Federation (RF) for the period between 2000 and 2018, in the Republic of Tatarstan – since 1998, submitted by the Rospotrebnadzor Administrations in the constituent entities of the Russian Federation, materials of the Center for Hygiene and Epidemiology in the Republic of Tatarstan and the Main Veterinary Administration of the Republic of Tatarstan.</p></sec><sec><title>Results and discussion</title><p>Results and discussion. We have carried out the analysis of the epidemiological situation in the Republic of Tatarstan for the period of 1998–2018, by the administrative territories of the republic. The incidence of human leptospirosis caused by various leptospira serogroups has been assessed. In total, 112 people got infected with leptospirosis during the analyzed period. Also the data of epizootiological survey of small mammals inhabiting the natural foci of leptospirosis in the republic are presented. Laboratory tests of 1565 samples from mouse-like rodents for the presence of leptospirosis pathogens have been performed. 1.9 % of the tests gave a positive result. Dominant in the Republic of Tatarstan are the serogroups of Leptospira – Leptospira grippotyphosa and L. hebdomadis. The results of laboratory studies on the carriage of leptospira among small mammals and contamination of environmental objects indicate the circulation of pathogens of leptospirosis in the population of small mammals, habitant in forest shrub, near-water and meadow field stations of the republic. The red vole prevails in this community, the average index of its dominance is 66.7 %. Epizootiological monitoring point to a latent epizootic process in the community of mouse-like rodents.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>лептоспироз</kwd><kwd>серогруппы лептоспир</kwd><kwd>эпидемиологическая ситуация</kwd><kwd>эпизоотологический мониторинг</kwd></kwd-group><kwd-group xml:lang="en"><kwd>leptospirosis</kwd><kwd>leptospira serogroups</kwd><kwd>epidemiological situation</kwd><kwd>epizootiological monitoring</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Moore G.E., Guptill L.F., Glickman N.W., Caldanaro R.J., Aucoin D., Glickman L.T. Canine leptospirosis, United States, 2002–2004. Emerg. Infect. Dis. 2006; 12(3):501–3. DOI: 10.3201/eid1203.050809.</mixed-citation><mixed-citation xml:lang="en">Moore G.E., Guptill L.F., Glickman N.W., Caldanaro R.J., Aucoin D., Glickman L.T. Canine leptospirosis, United States, 2002–2004. Emerg. 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