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<article article-type="review-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">microbe</journal-id><journal-title-group><journal-title xml:lang="ru">Проблемы особо опасных инфекций</journal-title><trans-title-group xml:lang="en"><trans-title>Problems of Particularly Dangerous Infections</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0370-1069</issn><issn pub-type="epub">2658-719X</issn><publisher><publisher-name>Russian Research Anti-Plague Institute “Microbe”</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21055/0370-1069-2026-2-18-33</article-id><article-id custom-type="elpub" pub-id-type="custom">microbe-2341</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group></article-categories><title-group><article-title>Иксодовые клещевые боррелиозы в мире. Эпидемиологическая ситуация в Российской Федерации в 2025 г. в сравнении с многолетними данными и прогноз на 2026 г.</article-title><trans-title-group xml:lang="en"><trans-title>Ixodidae Tick-Borne Borrelioses in the World. Epidemiological Situation in the Russian Federation in 2025 in Comparison with Long-Term Data and Forecast for 2026</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7220-4366</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пеньевская</surname><given-names>Н. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Pen’evskaya</surname><given-names>N. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>644080, Омск, пр. Мира, 7;Омск, ул. Ленина, 12</p></bio><bio xml:lang="en"><p>7, Mira Avenue, Omsk, 644080;12, Lenina St., Omsk</p></bio><email xlink:type="simple">nap20052005@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1897-5522</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Теслова</surname><given-names>О. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Teslova</surname><given-names>O. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>644080, Омск, пр. Мира, 7;Омск, ул. Ленина, 12</p></bio><bio xml:lang="en"><p>7, Mira Avenue, Omsk, 644080;12, Lenina St., Omsk</p></bio><email xlink:type="simple">mail@oniipi.org</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8267-7012</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кузьменко</surname><given-names>Ю. Ф.</given-names></name><name name-style="western" xml:lang="en"><surname>Kuz’menko</surname><given-names>Yu. F.</given-names></name></name-alternatives><bio xml:lang="ru"><p>644080, Омск, пр. Мира, 7;Омск, ул. Ленина, 12</p></bio><bio xml:lang="en"><p>7, Mira Avenue, Omsk, 644080;12, Lenina St., Omsk</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0756-2271</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Блох</surname><given-names>А. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Blokh</surname><given-names>A. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>644080, Омск, пр. Мира, 7;Омск, ул. Ленина, 12</p></bio><bio xml:lang="en"><p>7, Mira Avenue, Omsk, 644080;12, Lenina St., Omsk</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9566-9214</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рудаков</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Rudakov</surname><given-names>N. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>644080, Омск, пр. Мира, 7;Омск, ул. Ленина, 12</p></bio><bio xml:lang="en"><p>7, Mira Avenue, Omsk, 644080;12, Lenina St., Omsk</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4896-9369</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Транквилевский</surname><given-names>Д. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Trankvilevsky</surname><given-names>D. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>117105, Москва, Варшавское шоссе, 19а;Москва</p></bio><bio xml:lang="en"><p>19a, Varshavskoe Highway, Moscow, 117105;Moscow</p></bio><email xlink:type="simple">gsen@fcgie.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4509-1212</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Штрек</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Shtrek</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>644080, Омск, пр. Мира, 7;Омск, ул. Ленина, 12</p></bio><bio xml:lang="en"><p>7, Mira Avenue, Omsk, 644080;12, Lenina St., Omsk</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0920-0100</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Савельев</surname><given-names>Д. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Savel’ev</surname><given-names>D. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>644080, Омск, пр. Мира, 7</p></bio><bio xml:lang="en"><p>7, Mira Avenue, Omsk, 644080</p></bio><email xlink:type="simple">mail@oniipi.org</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Омский научно-исследовательский институт природно-очаговых инфекций;&#13;
Омский государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Omsk Research Institute of Natural-Focal Infections;&#13;
Omsk State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Федеральный центр гигиены и эпидемиологии;&#13;
Институт дезинфектологии ФБУН «ФНЦГ им. Ф.Ф. Эрисмана»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal Center of Hygiene and Epidemiology;&#13;
Institute of Disinfectology of the Federal Scientific Center of Hygiene named after F.F. Erisman</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Омский научно-исследовательский институт природно-очаговых инфекций</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Omsk Research Institute of Natural-Focal Infections</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2026</year></pub-date><pub-date pub-type="epub"><day>22</day><month>07</month><year>2026</year></pub-date><volume>0</volume><issue>2</issue><fpage>18</fpage><lpage>33</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Пеньевская Н.А., Теслова О.Е., Кузьменко Ю.Ф., Блох А.И., Рудаков Н.В., Транквилевский Д.В., Штрек С.В., Савельев Д.А., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Пеньевская Н.А., Теслова О.Е., Кузьменко Ю.Ф., Блох А.И., Рудаков Н.В., Транквилевский Д.В., Штрек С.В., Савельев Д.А.</copyright-holder><copyright-holder xml:lang="en">Pen’evskaya N.A., Teslova O.E., Kuz’menko Y.F., Blokh A.I., Rudakov N.V., Trankvilevsky D.V., Shtrek S.V., Savel’ev D.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.microbe.ru/jour/article/view/2341">https://journal.microbe.ru/jour/article/view/2341</self-uri><abstract><p>Представлен обзор эпидемиологической обстановки по иксодовым клещевым боррелиозам (ИКБ) в мире и Российской Федерации в 2025 г. в сравнении с многолетними данными, дан прогноз на 2026 г. В 2025 г. в РФ зарегистрировано максимальное число случаев ИКБ (9698) за последние 15 лет. Относительно среднемноголетних значений показатели заболеваемости ИКБ выросли в четырех федеральных округах: Центральном (ЦФО), Приволжском, Южном (ЮФО) и Северо-Кавказском (СКФО); значительно увеличился удельный вес ЦФО в общей структуре заболеваемости ИКБ (55,43 %); увеличилось до 84 число субъектов с регистрируемой заболеваемостью ИКБ, в половине из них отмечен рост инцидентности. На протяжении периода 2013–2025 гг. сохраняются особенности тенденций эпидемического процесса ИКБ на территориях различной степени эпидемиологического риска. В большинстве субъектов со среднемноголетним показателем заболеваемости (СМП) на 100 тыс. населения выше 8,4 0 /0000 выявлена тенденция к снижению или относительная стабильность заболеваемости ИКБ, кроме г. Москвы и Калужской области, где отмечен выраженный тренд к росту. В 10 из 19 регионов с СМП от 4,2 до 8,3 0 /0000 отмечена тенденция к росту, а в 8 – к снижению заболеваемости. Тренд к росту заболеваемости ИКБ выявлен в 14 из 24 субъектов с СМП от 1,6 до 4,1 0 /0000 и в 19 из 29 регионов с низким СМП (до 1,5 0 /0000). Проведенный анализ тенденций развития эпидемического процесса и расчеты вероятного уровня заболеваемости позволяют заключить, что для большинства федеральных округов уровень заболеваемости ИКБ в 2026 г. будет варьировать около доверительных интервалов среднемноголетних значений, за исключением ЦФО, ЮФО и СКФО, где возможен рост числа случаев ИКБ. Эффективный контроль эпидемической ситуации по ИКБ возможен при условии сохранения и совершенствования, а для таких регионов, как г. Москва, г. Санкт-Петербург, Московская, Воронежская, Липецкая, Нижегородская, Костромская, Рязанская, Тульская, Калужская, Брянская, Кировская, Курская, Орловская, Тверская, Тюменская, Пензенская и Иркутская области, Алтайский и Забайкальский края, республики Бурятия и Мордовия, субъекты ЮФО и СКФО, – увеличения объемов и повышения качества профилактических мероприятий, включая гигиеническое воспитание и обучение населения, усиление зоологоэнтомологического мониторинга активности и структуры природных очагов.</p></abstract><trans-abstract xml:lang="en"><p>An overview of the epidemiological situation on Ixodidae tick-borne borreliosis (ITBB) in the world and the Russian Federation in 2025 in comparison with long-term values is presented. A forecast for 2026 is made. In 2025, the maximum number of ITBB cases was registered in the Russian Federation (9,698) over the past 15 years. Relative to the long-term average, the incidence rates of ITBB increased in 4 federal districts: Central (CFD), Volga, Southern (SFD) and North-Caucasian (NCFD) ones; the proportion of CFD in the overall structure of ITBB incidence expanded significantly (55.43 %). The number of constituent entities with a reported incidence of ITBB has risen to 84, and an increase in incidence has been noted in half of them. During the period of 2013–2025, the peculiarities of trends in the epidemic process of ITBB in territories of varying degrees of epidemiological risk persisted. In the majority of entities with a long-term average annual incidence (LTAA) above 8.4 0 /0000, a downward trend or relative stability in the incidence of ITBB has been revealed, with the exception of Moscow and the Kaluga Region, where a pronounced upward trend was noted. In 10 out of 19 regions with LTAA between 4.2 and 8.3 0 /0000, an upward trend was observed, while in 8 – a decrease in morbidity. The trend towards an increase in the incidence of ITBB was detected in 14 out of 24 entities with LTAA from 1.6 to 4.1 0 /0000 and in 19 of the 29 regions with low LTAA (up to 1.5 0 /0000). The analysis of trends in the development of the epidemic process and calculations of the probable incidence rate allows us to conclude that for most federal districts, the incidence rate of ITBB in 2026 will vary around the confidence intervals of the long-term average values, with the exception of the CFD, SFD and NCFD, where an increase in the number of cases of ITBB is probable. Effective control of the epidemic situation on ITBB is possible provided that it is maintained and enhanced. For regions such as Moscow, Saint Petersburg; Moscow, Voronezh, Lipetsk, Nizhny Novgorod, Kostroma, Ryazan, Tula, Kaluga, Bryansk, Kirov, Kursk, Orel, Tver, Tyumen, Penza and Irkutsk Regions, Altai and Trans-Baikal Territories, the Republics of Buryatia and Mordovia, constituent entities of the Southern Federal District and the North-Caucasian Federal District, increase in the volume and improvement of the quality of preventive measures, including hygienic education of the population, strengthening zoological and entomological monitoring of the activity and structure of natural foci, are required.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>иксодовые клещевые боррелиозы (болезнь Лайма)</kwd><kwd>эпидемиологический надзор</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Ixodidae tick-borne borreliosis (Lyme disease)</kwd><kwd>epidemiological surveillance</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Коренберг Э.И., Помелова В.Г., Осин Н.С. 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