microbeПроблемы особо опасных инфекцийProblems of Particularly Dangerous Infections0370-10692658-719XRussian Research Anti-Plague Institute “Microbe”10.21055/0370-1069-2018-1-5-11microbe-452Research ArticleОБЗОРЫREVIEWSНодулярный дерматит: появление новой поксвирусной инфекции в РоссииNodular Dermatitis: Emergence of Novel Poxviral Infection in RussiaБорисевичС. В.BorisevichS. V.

Сергиев Посад.

Sergiev Possad.

48cnii@mil.ruСизиковаТ. Е.SizikovaT. E.

Сергиев Посад.

Sergiev Possad.

ПетровА. А.PetrovA. A.

Сергиев Посад.

Sergiev Possad.

КарулинА. В.KarulinA. V.

Сергиев Посад.

Sergiev Possad.

ЛебедевВ. Н.LebedevV. N.

Сергиев Посад.

Sergiev Possad.

ФГБУ «48 Центральный научно-исследовательский институт» Министерства обороны Российской Федерации.Россия48th Central Research Institute of the Ministry of Defense of the Russian Federation.Russian Federation20180704201801511Copyright © Борисевич С.В., Сизикова Т.Е., Петров А.А., Карулин А.В., Лебедев В.Н., 20182018Борисевич С.В., Сизикова Т.Е., Петров А.А., Карулин А.В., Лебедев В.Н.Borisevich S.V., Sizikova T.E., Petrov A.A., Karulin A.V., Lebedev V.N.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.microbe.ru/jour/article/view/452

Нодулярный дерматит представляет собой экзотическое для россии поксвирусное заболевание. В обзоре рассмотрены отдельные эпизоотологические характеристики нодулярного дерматита, вопросы лабораторной диагностики заболевания, возможные причины расширения ареала распространения возбудителя, а также проведен филогенетический анализ нуклеотидных последовательностей гена РЗ2 вируса нодулярного дерматита. Отмечено, что с учетом экономического урона, вызываемого нодулярным дерматитом, чтобы не допустить возможности его распространения в неэнзоотические регионы необходимо активно использовать существующие эффективные средства специфической профилактики. Быстрое расширение ареала распространения нодулярного дерматита на территории РФ следует расценивать как фактор, несущий угрозу биологической безопасности страны.

Nodular dermatitis, (dermatitis nodularis), is an exotic for the Russian Federation poxviral disease. Some epizootical characteristics of it, problems of laboratory diagnostics, and possible reasons of extension of agent spread areal are discussed in this review. Phylogenetic analysis of P32 gene nucleotide sequences of dermatitis nodularis virus has also been conducted. It is noted that taking into account the economic loss caused by the disease and possibility of its import into non-enzootic regions, it is necessary to use existing effective means of specific prophylacsis extensively. The swift outspread of the disease in the Russian Federation should be considered as the risk factor for biological safety of our country.

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The authors declare that there are no conflicts of interest present.