microbeПроблемы особо опасных инфекцийProblems of Particularly Dangerous Infections0370-10692658-719XRussian Research Anti-Plague Institute “Microbe”10.21055/0370-1069-2011-1(107)-53-57microbe-588Research ArticleМИКРОБИОЛОГИЯMICROBIOLOGYАнтибиотикоустойчивые штаммы возбудителя чумы и разработка способа их детекции методом полимеразной цепной реакцииAntibiotic-Resistant Strains of Plague Agent and Development of Procedure for Their Detection by PCR MethodЕрошенкоГ. А.EroshenkoG. A.microbe@san.ruОдиноковГ. Н.OdinokovG. N.noemail@neicon.ruАнисимоваЛ. В.AnisimovaL. V.noemail@neicon.ruШавинаН. Ю.ShavinaN. Yu.noemail@neicon.ruВиноградоваН. А.VinogradovaN. A.noemail@neicon.ruКутыревВ. В.KutyrevV. V.noemail@neicon.ruРоссийский научно-исследовательский противочумный институт «Микроб»РоссияRussian Research Anti-Plague Institute MicrobeRussian Federation20112002201101(107)5357Copyright © Ерошенко Г.А., Одиноков Г.Н., Анисимова Л.В., Шавина Н.Ю., Виноградова Н.А., Кутырев В.В., 20112011Ерошенко Г.А., Одиноков Г.Н., Анисимова Л.В., Шавина Н.Ю., Виноградова Н.А., Кутырев В.В.Eroshenko G.A., Odinokov G.N., Anisimova L.V., Shavina N.Y., Vinogradova N.A., Kutyrev V.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.microbe.ru/jour/article/view/588

В работе приведены данные об антибиотикоустойчивых штаммах Yersinia pestis, выделенных из клинических источников и от животных, и показаны причины их резистентности к различным лекарственным препаратам. Сообщается о разработке двух ПЦР для выявления генов устойчивости к антибиотикам, эффективность которых подтверждена при использовании коллекции антибиотикоустойчивых штаммов Y. pestis.

The data of antibiotic-resistant strains of Yersinia pestis isolated from clinical sources and animals are shown in the present study. Highlighted are the reasons of their resistance to different drugs. Represented are two PCRs developed for detection of antibiotic resistance genes, their efficiency has been confirmed using collection of antibiotic-resistant strains of Y. pestis.

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The authors declare that there are no conflicts of interest present.