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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">microbe</journal-id><journal-title-group><journal-title xml:lang="ru">Проблемы особо опасных инфекций</journal-title><trans-title-group xml:lang="en"><trans-title>Problems of Particularly Dangerous Infections</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0370-1069</issn><issn pub-type="epub">2658-719X</issn><publisher><publisher-name>Russian Research Anti-Plague Institute “Microbe”</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21055/0370-1069-2013-4-48-50</article-id><article-id custom-type="elpub" pub-id-type="custom">microbe-77</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>МИКРОБИОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>MICROBIOLOGY</subject></subj-group></article-categories><title-group><article-title>Холерные вибрионы не О1/не О139, выделенные в ходе мониторинга водоемов и стоков Ростова-на-Дону с 2009 по 2011 год</article-title><trans-title-group xml:lang="en"><trans-title>Cholera Vibrios non-O1/non-O139 Isolated in the Process of Epidemiological Monitoring over Rostov-on-Don Water Basins and Drain Sewage System within the Period of 2009–2011</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Григоренко</surname><given-names>Л. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Grigorenko</surname><given-names>L. V.</given-names></name></name-alternatives><email xlink:type="simple">plague@aaanet.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кругликов</surname><given-names>В. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Kruglikov</surname><given-names>V. D.</given-names></name></name-alternatives><email xlink:type="simple">plague@aaanet.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мазрухо</surname><given-names>А. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Mazrukho</surname><given-names>A. B.</given-names></name></name-alternatives><email xlink:type="simple">plague@aaanet.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Архангельская</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Arkhangel’Skaya</surname><given-names>I. V.</given-names></name></name-alternatives><email xlink:type="simple">plague@aaanet.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зубкова</surname><given-names>Д. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Zubkova</surname><given-names>D. A.</given-names></name></name-alternatives><email xlink:type="simple">plague@aaanet.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Непомнящая</surname><given-names>Н. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Nepomnyashchaya</surname><given-names>N. B.</given-names></name></name-alternatives><email xlink:type="simple">plague@aaanet.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шестиалтынова</surname><given-names>И. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Shestialtynova</surname><given-names>I. S.</given-names></name></name-alternatives><email xlink:type="simple">plague@aaanet.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Ростовский-на-Дону научно-исследовательский противочумный институт</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Rostov-on-Don Research Anti-Plague Institute</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2013</year></pub-date><pub-date pub-type="epub"><day>20</day><month>12</month><year>2013</year></pub-date><volume>0</volume><issue>4</issue><fpage>48</fpage><lpage>50</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Григоренко Л.В., Кругликов В.Д., Мазрухо А.Б., Архангельская И.В., Зубкова Д.А., Непомнящая Н.Б., Шестиалтынова И.С., 2013</copyright-statement><copyright-year>2013</copyright-year><copyright-holder xml:lang="ru">Григоренко Л.В., Кругликов В.Д., Мазрухо А.Б., Архангельская И.В., Зубкова Д.А., Непомнящая Н.Б., Шестиалтынова И.С.</copyright-holder><copyright-holder xml:lang="en">Grigorenko L.V., Kruglikov V.D., Mazrukho A.B., Arkhangel’Skaya I.V., Zubkova D.A., Nepomnyashchaya N.B., Shestialtynova I.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.microbe.ru/jour/article/view/77">https://journal.microbe.ru/jour/article/view/77</self-uri><abstract><p>Изучены биологические свойства холерных вибрионов не О1/не О139, циркулирующих в поверхностных водоемах и стоках Ростова-на-Дону с 2009 по 2011 год. Подавляющее большинство изолятов были типичны по фенотипу. Из 280 штаммов у 90 выделенных штаммов (21 %) выявлена атипичность по агглютинабельности в реакции слайд-агглютинации на стекле и в развернутой РА с холерными диагностическими сыворотками. Даны рекомендации по дифференциации V. cholerae non О1/ non О139 от V. cholerae О1 и О139. Установлены доминирующие серогруппы (О16, О53, О76 и О67), которые за указанный период не менялись. Определена вариабельность генотипов штаммов и низкая вероятность проявления вирулентности. Показана нецелесообразность проведения сплошного гено- и серологического типирования водных штаммов.</p></abstract><trans-abstract xml:lang="en"><p>Studied have been biological properties of cholera vibrios non-O1/non-O139 circulating in the Rostov-on-Don surface waters and drain sewage system within the period of 2009–2011. Overwhelming majority of the isolates have been classified as typical ones in terms of their phenotype. However 90 strains (21 %) out of total 280 have been identified as atypical ones against agglu­tina­bility in the slide-agglutination and full-scale agglutination reaction to diagnostic cholera sera. Put forward are recommendations on performance of the differentiation between V. cholerae non-O1/non-O139 and V. cholerae O1/O139. Specified are predominant sero­groups of the strains which turned to be unchanged within the stated period (O16, O53, O76, and O67). Revealed is the strain genotype variability and low probability of virulence manifestations. Demonstrated is the futility of the blind gene- and serological typing of aquatic strains.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>холерные вибрионы не О1/не О139</kwd><kwd>фенотип</kwd><kwd>агглютинабельность</kwd><kwd>атипичность</kwd><kwd>серогруппы</kwd><kwd>генотип</kwd><kwd>cholera vibrios non-O1/nonO139</kwd><kwd>phenotype</kwd><kwd>agglutinability</kwd><kwd>typicality</kwd><kwd>serogroup</kwd><kwd>genotype</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Авдеева Е.П., Мазрухо Б.Л., Ишина Е.В., Воронежская Л.Г. Оценка метода серологической идентификации Vibrio cholerae не О1. Журн. микробиол., эпидемиол. и иммунобиол. 2001; 4:75–8.</mixed-citation><mixed-citation xml:lang="en">Avdeeva E.P., Mazrukho B.L., Ishina E.V., Voronezhskaya L.G. [Evaluation of the methodology for serological Vibrio cholerae non-O1 identification]. Zh. Mikrobiol. Epidemiol. 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