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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">microbe</journal-id><journal-title-group><journal-title xml:lang="ru">Проблемы особо опасных инфекций</journal-title><trans-title-group xml:lang="en"><trans-title>Problems of Particularly Dangerous Infections</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0370-1069</issn><issn pub-type="epub">2658-719X</issn><publisher><publisher-name>Russian Research Anti-Plague Institute “Microbe”</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21055/0370-1069-2012-3-102-103</article-id><article-id custom-type="elpub" pub-id-type="custom">microbe-843</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КРАТКИЕ СООБЩЕНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>BRIEF COMMUNICATIONS</subject></subj-group></article-categories><title-group><article-title>Анализ SXT констина антибиотикочувствительного штамма 
                  Vibrio choleraе неО1/неО139 серогруппы</article-title><trans-title-group xml:lang="en"><trans-title>Analysis of the SXT Constin of Antibiotic-Sensitive 
                  Vibrio cholerae Strain of Non-O1/ Non-O139 Serogroup</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Фадеева</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Fadeeva</surname><given-names>A. V.</given-names></name></name-alternatives><email xlink:type="simple">rusrapi@microbe.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ерошенко</surname><given-names>Г. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Eroshenko</surname><given-names>G. A.</given-names></name></name-alternatives><email xlink:type="simple">rusrapi@microbe.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шавина</surname><given-names>Н. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Shavina</surname><given-names>N. Yu.</given-names></name></name-alternatives><email xlink:type="simple">rusrapi@microbe.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кутырев</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kutyrev</surname><given-names>V. V.</given-names></name></name-alternatives><email xlink:type="simple">rusrapi@microbe.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Российский научно-исследовательский противочумный институт «Микроб»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian Research Anti-Plague Institute “Microbe”</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2012</year></pub-date><pub-date pub-type="epub"><day>20</day><month>06</month><year>2012</year></pub-date><volume>0</volume><issue>3(113)</issue><fpage>102</fpage><lpage>103</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Фадеева А.В., Ерошенко Г.А., Шавина Н.Ю., Кутырев В.В., 2012</copyright-statement><copyright-year>2012</copyright-year><copyright-holder xml:lang="ru">Фадеева А.В., Ерошенко Г.А., Шавина Н.Ю., Кутырев В.В.</copyright-holder><copyright-holder xml:lang="en">Fadeeva A.V., Eroshenko G.A., Shavina N.Y., Kutyrev V.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.microbe.ru/jour/article/view/843">https://journal.microbe.ru/jour/article/view/843</self-uri><abstract><p>В геноме антибиотикочувствительного штамма 
                  Vibrio 
                  cholerae серогруппы О50, выделенного в России в 1974 г., выявлено наличие SXT конъюгативного транспозона (SXT констина). Анализ его структуры показал, что он не содержит генов устойчивости к антибиотикам – стрептомицину, сульфаметоксазолу, триметоприму, хлорамфениколу и канамицину и, по-видимому, относится к числу предшественников антибиотикорезистентных SXT констинов, получивших распространение в геномах эпидемических штаммов 
                  V. 
                  cholerae О139 в 1992 г.</p></abstract><trans-abstract xml:lang="en"><p>In the genome of antibiotic-sensitive 
                  Vibrio cholerae strain belonging to O50 serogroup, isolated in the territory of the Russian Federation in 1974, detected is the SXT conjugative trasposone – SXT constin. Analysis if its structure revealed that it does not contain genes of resistance to such antibiotics as streptomycin, sulfamethoxasole, trimethoprim, chloramphenicol, and kanamycin, being, probably, one of the predecessors of antibiotic-resistant SXT constins which spread out within the genomes of epidemic 
                  Vibrio cholerae O139 strains in 1992.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>возбудитель холеры</kwd><kwd>геном</kwd><kwd>устойчивость к антибиотикам</kwd><kwd>cholera agent</kwd><kwd>genome</kwd><kwd>antibiotic resistance</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Ерошенко Г.А., Одиноков Г.Н., Анисимова Л.В., Шавина Н.Ю., Виноградова Н.А., Кутырев В.В. Антибиотикоустойчивые штаммы возбудителя чумы и разработка способа их детекции методом полимеразной цепной реакции. Пробл. особо опасных инф. 2011; 1(107):53–7.</mixed-citation><mixed-citation xml:lang="en">Eroshenko G.A., Odinokov G.N., Anisimova L.V., Shavina N.Yu., Vinogradova N.A., Kutyrev V.V. [Antibiotic-resistant strains of plague agent and development of procedure for their detection by PCR method]. Probl. Osobo. Opasn. Infek. 2011; (107):53–7.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Hochhut B., Lotfi Y., Mazel D., Faruque S.M., Woodgate R., Waldor M.K. Molecular analysis of antibiotic resistance gene clusters in Vibrio cholerae O139 and O1 constins. Antimicrob. Agents Chemother. 2001; 45:2991–3000.</mixed-citation><mixed-citation xml:lang="en">Hochhut B., Lotfi Y., Mazel D., Faruque S.M., Woodgate R., Waldor M.K. Molecular analysis of antibiotic resistance gene clusters in Vibrio cholerae O139 and O1 constins. Antimicrob. Agents Chemother. 2001; 45:2991–3000.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
