Preview

Problems of Particularly Dangerous Infections

Advanced search

Analysis of the Epizootic and Epidemiological Situation on Leptospirosis in 2023 and Forecast for 2024 in the Russian Federation

https://doi.org/10.21055/0370-1069-2024-3-51-62

Abstract

The aim of the work was to analyze the epizootic and epidemiological situation on leptospirosis in the territory of the Russian Federation in 2023 and to forecast its development for 2024. In the period between 2000 and 2023, the long-term dynamics of morbidity in Russia tended to decrease. Leptospirosis incidence was mainly sporadic. In 2023, cases of this infection in humans were reported in all federal districts, with the exception of the North Caucasian one. The highest incidence rates were recorded in the Southern and Central Federal Districts. The results of testing material from small mammals using bacteriological, immunological and molecular-biological methods confirmed the circulation of pathogenic Leptospira in 50 constituent entities of the Russian Federation in all federal districts. Specific prevention measures were carried out: 20,114 people were vaccinated in 27 entities. The probability of human infection is higher in the territories of the Southern, Central, Northwestern, Volga and Ural Federal Districts. Imported cases of infection from regions with subequatorial and equatorial climates, which are actively visited by tourists, are not excluded.

About the Authors

D. V. Trankvilevsky
Federal Center of Hygiene and Epidemiology; Federal Scientific Center of Hygiene named after F.F. Erisman
Russian Federation

19a, Varshavskoe Highway, Moscow, 117105, Russian Federation



O. N. Skudareva
Federal Service for Surveillance on Consumers’ Rights Protection and Human Well-being
Russian Federation

18, Bld. 5 and 7, Vadkovsky Lane, Moscow, 127994, Russian Federation



E. P. Igonina
Federal Service for Surveillance on Consumers’ Rights Protection and Human Well-being
Russian Federation

18, Bld. 5 and 7, Vadkovsky Lane, Moscow, 127994, Russian Federation



E. Yu. Kiseleva
Irkutsk Research Anti-Plague Institute of Siberia and the Far East
Russian Federation

78, Trilissera St., Irkutsk, 664047, Russian Federation



V. M. Korzun
Irkutsk Research Anti-Plague Institute of Siberia and the Far East
Russian Federation

78, Trilissera St., Irkutsk, 664047, Russian Federation



Yu. A. Verzhutskaya
Irkutsk Research Anti-Plague Institute of Siberia and the Far East
Russian Federation

78, Trilissera St., Irkutsk, 664047, Russian Federation



A. K. Noskov
Rostov-on-Don Research Anti-Plague Institute
Russian Federation

117/40, M. Gor’kogo St., Rostov-on-Don, 344002, Russian Federation



E. S. Kulikalova
Irkutsk Research Anti-Plague Institute of Siberia and the Far East
Russian Federation

78, Trilissera St., Irkutsk, 664047, Russian Federation



N. V. Breneva
Irkutsk Research Anti-Plague Institute of Siberia and the Far East
Russian Federation

78, Trilissera St., Irkutsk, 664047, Russian Federation



S. E. Budaeva
Irkutsk Research Anti-Plague Institute of Siberia and the Far East
Russian Federation

78, Trilissera St., Irkutsk, 664047, Russian Federation



I. V. Morozova
Rostov-on-Don Research Anti-Plague Institute
Russian Federation

117/40, M. Gor’kogo St., Rostov-on-Don, 344002, Russian Federation



A. V. Trishina
Rostov-on-Don Research Anti-Plague Institute
Russian Federation

117/40, M. Gor’kogo St., Rostov-on-Don, 344002, Russian Federation



References

1. Anan’in V.V., editor [Human and Animal Leptospirosis]. Moscow: “Medicine”; 1971. 352 p.

2. Soboleva G.L., Anan’ina Yu.V., Nepoklonova I.V. [Relevant issues of human and animal leptospirosis]. Rossijsky Veterinarny Zhurnal [Russian Veterinary Journal]. 2017; (8):14–8.

3. Gorodin V.N., Moysova D.L., Bakhtina V.A., Zotov S.V. [Trends of contemporary leptospirosis]. Epidemiologiya i Infektsionnye Bolezni [Epidemiology and Infectious Diseases]. 2018; 23(2):93–100. DOI: 10.18821/1560-9529-2018-23-2-93-100.

4. Anan’ina Yu.V. [Leptospira – causative agents of human leptospirosis]. In: Labinskaya A.S., Kostyukova N.N., Ivanova S.M., editors. [A Guide to Medical Microbiology. Special Medical Microbiology and Etiological Diagnostics of Infections]. Book II. Moscow: “BINOM Publishing House”; 2022. P. 821–43.

5. Costa F., Hagan J.E., Calcagno J., Kane M., Torgerson P., Martinez-Silveira M.S., Stein C., Abela-Ridder B., Ko A.I. Global morbidity and mortality of leptospirosis: a systematic review. PLoS Negl. Trop. Dis. 2015; 9(9):e0003898. DOI: 10.1371/journal.pntd.0003898.

6. Nau L.H., Emirhar D., Obiegala A., Mylius M., Runge M., Jacob J., Bier N., Nöckler K., Imholt C., Below D., Princk C., Dreesman J., Ulrich R.G., Pfeffer M., Mayer-Scholl A. Leptospirose in Deutschland: Aktuelle Erkenntnisse zu Erregerspezies, Reservoirwirten und Erkrankungen bei Mensch und Tier. Leptospirosis in Germany: current knowledge on pathogen species, reservoir hosts, and disease in humans and animals. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2019; 62(12):1510–21. DOI: 10.1007/s00103-019-03051-4.

7. Garcia-Lopez M., Lorioux C., Soares A., Trombert-Paolantoni S., Harran E., Ayral F., Picardeau M., Djelouadji Z., Bourhy P. Genetic diversity of Leptospira strains circulating in humans and dogs in France in 2019–2021. Front. Cell. Infect. Microbiol. 2023; 13:1236866. DOI: 10.3389/fcimb.2023.1236866.

8. Adler B., de la Peña Moctezuma A. Leptospira and leptospirosis. Vet. Microbiol. 2010; 140(3-4):287–96. DOI: 10.1016/j.vetmic.2009.03.012.

9. Trankvilevskiy D.V. [On about contamination of small mammals by zoonotic causative agents]. Zdorov’e Naseleniya i Sreda Obitaniya [Public Health and Life Environment]. 2016; (10):53–6.

10. European Surveillance System (TESSy). Leptospirosis. Annual Epidemiological Report for 2014–2021. Stockholm: ECDC; 2023. Available from: https://www.ecdc.europa.eu/en.

11. Mohd Radi M.F., Hashim J.H., Jaafar M.H., Hod R., Ahmad N., Mohammed Nawi A., Baloch G.M., Ismail R., Farakhin Ayub N.I. Leptospirosis outbreak after the 2014 major flooding event in Kelantan, Malaysia: A spatial-temporal analysis. Am. J. Trop. Med. Hyg. 2018; 98(5):1281–95. DOI: 10.4269/ajtmh.16-0922.

12. Kupek E., de Sousa Santos Faversani M.C., de Souza Philippi J.M. The relationship between rainfall and human leptospirosis in Florianópolis, Brazil, 1991–1996. Braz. J. Infect. Dis. 2000; 4(3):131–4.

13. Becirovic A., Trnacevic A., Dubinovic-Rekic A., Dzafic F. Floods associated with environmental factors and leptospirosis: our experience at Tuzla Canton, Bosnia and Herzegovina. Mater. Sociomed. 2022; 34(3):193–6. DOI: 10.5455/msm.2022.34.193-196.

14. Warnasekara J., Agampodi S. Neglecting the neglected during the COVID-19 pandemic: the case of leptospirosis in Sri Lanka. Epidemiol. Health. 2022; 44:e2022015. DOI: 10.4178/epih.e2022015.

15. Maskey M., Shastri J.S., Saraswathi K., Surpam R., Vaidya N. Leptospirosis in Mumbai: post-deluge outbreak 2005. Indian J. Med. Microbiol. 2006; 24(4):337–8. DOI: 10.4103/0255-0857.29413.

16. Matsushita N., Ng C.F.S., Kim Y., Suzuki M., Saito N., Ariyoshi K., Salva E.P., Dimaano E.M., Villarama J.B., Go W.S., Hashizume M. The non-linear and lagged short-term relationship between rainfall and leptospirosis and the intermediate role of floods in the Philippines. PLoS Negl. Trop. Dis. 2018; 12(4):e0006331. DOI: 10.1371/journal.pntd.0006331.

17. Dhewantara P.W., Mamun A., Zhang W.Y., Yin W.W., Ding F., Guo D., Hu W., Costa F., Ko A.I., Soares Magalhães R.J. Epidemiological shift and geographical heterogeneity in the burden of leptospirosis in China. Infect. Dis. Poverty. 2018; 7(1):57. DOI: 10.1186/s40249-018-0435-2.

18. Li J.M., Li L.M., Shi J.F., Li T., Wang Q., Ma Q.X., Zheng W., Feng H.F., Liu F., Du R. Prevalence of Leptospira in murine in China: A systematic review and meta-analysis. Front. Vet. Sci. 2022; 9:944282. DOI: 10.3389/fvets.2022.944282.

19. Hu W., Lin X., Yan J. Leptospira and leptospirosis in China. Curr. Opin. Infect. Dis. 2014; 27(5):432–6. DOI: 10.1097/QCO.0000000000000097.

20. Helman S.K., Tokuyama A.F.N., Mummah R.O., Stone N.E., Gamble M.W., Snedden C.E., Borremans B., Gomez A.C.R., Cox C., Nussbaum J., Tweedt I., Haake D.A., Galloway R.L., Monzón J., Riley S.P.D., Sikich J.A., Brown J., Friscia A., Sahl J.W., Wagner D.M., Lynch J.W., Prager K.C., Lloyd-Smith J.O. Pathogenic Leptospira are widespread in the urban wildlife of southern California. Sci. Rep. 2023; 13(1):14368. DOI: 10.1038/s41598-023-40322-2.

21. Browne E.S., Pereira M., Barreto A., Zeppelini C.G., de Oliveira D., Costa F. Prevalence of human leptospirosis in the Americas: a systematic review and meta-analysis. Rev. Panam. Salud Publica. 2023; 47:e126. DOI: 10.26633/RPSP.2023.126.

22. Hagiya H., Koyama T., Otsuka F. Epidemiological characteristics and trends in the incidence of leptospirosis in Japan: a nationwide, observational study from 2006 to 2021. Am. J. Trop. Med. Hyg. 2023; 109(3):589–94. DOI: 10.4269/ajtmh.23-0131.

23. Lisovsky A.A., Sheftel B.I., Savelyev A.P., Ermakov O.A., Kozlov Yu.A., Smirnov D.G., Stakheev V.V., Glazov D.M. [Mammals of Russia: List of Species and Applied Aspects. Proceedings of the Zoological Museum of Moscow State University]. Vol. 56. Moscow: “Association of Scientific Publications of the CMC”; 2019. 191 p.

24. Zaks L. [Statistical Estimation]. Moscow: “Statistica”; 1976. 600 p.

25. Savilov E.D., Astaf’ev V.A., Zhdanov S.N., Zarudnev E.A. [Epidemiological Analysis: Methods of Statistical Processing of the Material]. Novosibirsk: “Science Center”; 2011. 156 p.

26. Trankvilevsky D.V., Kiseleva E.Yu., Korzun V.M., Breneva N.V., Verzhutskaya Yu.A., Zarva I.D., Skudareva O.N., Balakhonov S.V. [Epizootiological and epidemiological situation on leptospirosis in the Russian Federation over the period of 2013–2022 and the forecast for 2023]. Problemy Osobo Opasnykh Infektsii [Problems of Particularly Dangerous Infections]. 2023; (3):43–50. DOI: 10.21055/0370-1069-2023-3-43-50.

27. Trankvilevsky D.V., Tsarenko V.A., Zhukov V.I. [The current state of epizootiological monitoring of natural foci of infections in the Russian Federation]. Meditsinskaya Parazitologiya i Parazitarnye Bolezni [Medical Parasitology and Parasitic Diseases]. 2016; (2):19–24.


Review

For citations:


Trankvilevsky D.V., Skudareva O.N., Igonina E.P., Kiseleva E.Yu., Korzun V.M., Verzhutskaya Yu.A., Noskov A.K., Kulikalova E.S., Breneva N.V., Budaeva S.E., Morozova I.V., Trishina A.V. Analysis of the Epizootic and Epidemiological Situation on Leptospirosis in 2023 and Forecast for 2024 in the Russian Federation. Problems of Particularly Dangerous Infections. 2024;(3):51-62. (In Russ.) https://doi.org/10.21055/0370-1069-2024-3-51-62

Views: 285


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 0370-1069 (Print)
ISSN 2658-719X (Online)