Stabilized Phase Variants of Vibrio cholerae El Tor P-18895
https://doi.org/10.21055/0370-1069-2015-1-67-70
Abstract
Produced have been stabilized phase variants of V. cholerae El Tor P-18895 (O- and rugose colonies). Frequency of reversion to initial ST-phenotype does not exceed 10 %. Identity of the origin is verified in VNTR. Evaluated has also been their activity by means of the following diagnostic tests: agglutination assay, sensitivity to diagnostic bacteriophages test, and studies of growth behavior in solid nutrient media. Stabilized variants of V. cholerae El Tor P-18895 can be deployed for further investigations of peculiarities of biofilm formation on various surfaces, bacterial resistance to environmental factors, and for the enhancement of methods for isolation of cholera vibrio variants from ambient environment.
About the Authors
O. V. Markina
Rostov-on-Don Research Anti-Plague Institute
Russian Federation
Russian Federation
A. I. Shelokhovich
Rostov-on-Don Research Anti-Plague Institute
Russian Federation
Russian Federation
A. N. Terent’Ev
Rostov-on-Don Research Anti-Plague Institute
Russian Federation
Russian Federation
O. A. Tatarenko
Rostov-on-Don Research Anti-Plague Institute
Russian Federation
Russian Federation
S. O. Vodop’Yanov
Rostov-on-Don Research Anti-Plague Institute
Russian Federation
Russian Federation
A. B. Mazrukho
Rostov-on-Don Research Anti-Plague Institute
Russian Federation
Russian Federation
L. D. Makedonova
Rostov-on-Don Research Anti-Plague Institute
Russian Federation
Russian Federation
D. I. Kaminsky
Rostov-on-Don Research Anti-Plague Institute
Russian Federation
Russian Federation
I. S. Shestialtynova
Rostov-on-Don Research Anti-Plague Institute
Russian Federation
Russian Federation
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Review
For citations:
Markina O.V., Shelokhovich A.I., Terent’Ev A.N., Tatarenko O.A., Vodop’Yanov S.O., Mazrukho A.B., Makedonova L.D., Kaminsky D.I., Shestialtynova I.S. Stabilized Phase Variants of Vibrio cholerae El Tor P-18895. Problems of Particularly Dangerous Infections. 2015;(1):67-70. (In Russ.) https://doi.org/10.21055/0370-1069-2015-1-67-70
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