Genotypes and Subtypes of Hepatitis B Virus Isolates in the Territory of Siberia
https://doi.org/10.21055/0370-1069-2011-3(109)-31-35
Abstract
Identified are the occurrence, serotypic and genotypic variations of Hepatitis B virus isolates (HBV) among the Novosibirsk region inhabitants (n=2000), native population of the Alarsk District of the Irkutsk Region (n=487) and Shuryshkarsk Township of the Yamalo-Nenets Autonomous District (n=657). Occurrence rate of hepatitis В surface antigen (HBsAg) among different groups of the Novosibirsk Region population varied within the limits of 3,6-35,0 %. It was 8,2 % in Alarsk District, and 3,2 % in Shuryshkarsk Township. HBV isolates of D genotype (92-97 %) prevail among the population of Siberia; few are the cases of A (1,7 %) and C (1,2-8 %) genotypes. The identified varying occurrence of HBV sub-genotypes and HBsAg subtypes in two aboriginal groups of Siberia (D3 sub-genotype and ayw2 subtype - in the Alarsk District, D2 and ayw3 - in Shuryshkarsk Township) suggests the existence of, at least, two isolated HBV virus populations, circulating among different groups of Siberia native population .
About the Authors
G. V. Kochneva
State Research Centre of Virology and Biotechnology Vector
Russian Federation
Russian Federation
V. A. Manuylov
Novosibirsk State University
Russian Federation
Russian Federation
I. G. Netesova
ZAO Vector-Best
Russian Federation
Russian Federation
E. V. Chub
State Research Centre of Virology and Biotechnology Vector
Russian Federation
Russian Federation
R. B. Bayandin
State Research Centre of Virology and Biotechnology Vector
Russian Federation
Russian Federation
G. F. Sivolobova
State Research Centre of Virology and Biotechnology Vector
Russian Federation
Russian Federation
A. A. Grazhdantseva
State Research Centre of Virology and Biotechnology Vector
Russian Federation
Russian Federation
S. V. Netesov
Novosibirsk State University
Russian Federation
Russian Federation
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Review
For citations:
Kochneva G.V., Manuylov V.A., Netesova I.G., Chub E.V., Bayandin R.B., Sivolobova G.F., Grazhdantseva A.A., Netesov S.V. Genotypes and Subtypes of Hepatitis B Virus Isolates in the Territory of Siberia. Problems of Particularly Dangerous Infections. 2011;(3(109)):31-35. (In Russ.) https://doi.org/10.21055/0370-1069-2011-3(109)-31-35
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