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Prospects for Application of Ultrafiltration Technology for the Scaled Preparation of Plague Microbe and Cholera Vibrio Major Antigens

https://doi.org/10.21055/0370-1069-2011-3(109)-84-87

Abstract

Demonstrated is the possibility of application of ultrafiltration technologies in the process of cholera toxin and plague agent capsular antigen precipitation under production conditions. Application of ultrafiltration techniques permits of the reduction of losses at the stages of isolation and purification of antigen preparations; and concentration of raw material or semi-finished product provides for the reduction of labor inputs. Thus it leads to the increase in productivity and economical efficiency.

About the Authors

I. A. Shepelev
Russian Research Anti-Plague Institute Microbe
Russian Federation


S. A. Eremin
Russian Research Anti-Plague Institute Microbe
Russian Federation


Yu. G. Vasin
Russian Research Anti-Plague Institute Microbe
Russian Federation


O. A. Volokh
Russian Research Anti-Plague Institute Microbe
Russian Federation


T. V. Alenkina
Russian Research Anti-Plague Institute Microbe
Russian Federation


N. I. Belyakova
Russian Research Anti-Plague Institute Microbe
Russian Federation


E. M. Kuznetsova
Russian Research Anti-Plague Institute Microbe
Russian Federation


A. K. Nikiforov
Russian Research Anti-Plague Institute Microbe
Russian Federation


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Review

For citations:


Shepelev I.A., Eremin S.A., Vasin Yu.G., Volokh O.A., Alenkina T.V., Belyakova N.I., Kuznetsova E.M., Nikiforov A.K. Prospects for Application of Ultrafiltration Technology for the Scaled Preparation of Plague Microbe and Cholera Vibrio Major Antigens. Problems of Particularly Dangerous Infections. 2011;(3(109)):84-87. (In Russ.) https://doi.org/10.21055/0370-1069-2011-3(109)-84-87

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ISSN 0370-1069 (Print)
ISSN 2658-719X (Online)