Liposomal and Suspension Forms of Immunoglobulins Against Ebola Fever as the New Medical Preparations
https://doi.org/10.21055/0370-1069-2011-4(110)-57-60
Abstract
Presented are the results of investigation of therapeutic effectiveness of liposomal and suspension forms of immunoglobulins, prepared on the basis of 10 % goat immunoglobulin against Ebola fever. The most pronounced therapeutic and preventive effect on guinea pigs with experimental Ebola fever was achieved by double administration of suspended immunoglobulin against Ebola fever. The incubation period increased twofold, 37,5 % of infected animals survived. The results achieved are perspective for further development of new immunoglobulin preparations on the basis of liposomes and nanoemulsions.
Keywords
616.92/.93:615.12
About the Authors
N. M. Zubavichene
State Research Centre of Virology and Biotechnology Vector
Russian Federation
Russian Federation
V. V. Zolin
State Research Centre of Virology and Biotechnology Vector
Russian Federation
Russian Federation
E. A. Stavsky
State Research Centre of Virology and Biotechnology Vector
Russian Federation
Russian Federation
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Review
For citations:
Zubavichene N.M., Zolin V.V., Stavsky E.A. Liposomal and Suspension Forms of Immunoglobulins Against Ebola Fever as the New Medical Preparations. Problems of Particularly Dangerous Infections. 2011;(4(110)):57-60. (In Russ.) https://doi.org/10.21055/0370-1069-2011-4(110)-57-60
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