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Development of the Immuno-Enzyme Test-System for the Detection of Legionella pheumophila, Serogroup I

https://doi.org/10.21055/0370-1069-2011-4(110)-61-64

Abstract

Developed is the highly sensitive and specific immuno-enzyme test-system, which is perspective for the detection of L. pneumophilia, serogroup 1. Isolated are the three hybrid cell lines that secrete monoclonal antibodies to specific epitopes of L. pneumophilia, serogroup 1 lipopolysaccharide antigen. Hyper immune rabbit sera, characterized by highly specific activity and specificity, are obtained using lipopolysaccharide antigen.

About the Authors

G. V. Kuklina
Research Centre of Biosecurity of the 33rd Central Research and Probation Institute of the Ministry of Defense of the Russian Federation
Russian Federation


O. O. Fomenkov
Research Centre of Biosecurity of the 33rd Central Research and Probation Institute of the Ministry of Defense of the Russian Federation
Russian Federation


G. D. Elagin
Research Centre of Biosecurity of the 33rd Central Research and Probation Institute of the Ministry of Defense of the Russian Federation
Russian Federation


D. A. Kutaev
Research Centre of Biosecurity of the 33rd Central Research and Probation Institute of the Ministry of Defense of the Russian Federation
Russian Federation


D. S. Yanov
Research Centre of Biosecurity of the 33rd Central Research and Probation Institute of the Ministry of Defense of the Russian Federation
Russian Federation


A. A. Kytmanov
Research Centre of Biosecurity of the 33rd Central Research and Probation Institute of the Ministry of Defense of the Russian Federation
Russian Federation


N. V. Bogacheva
Research Centre of Biosecurity of the 33rd Central Research and Probation Institute of the Ministry of Defense of the Russian Federation
Russian Federation


T. P. Vorob'eva
Research Centre of Biosecurity of the 33rd Central Research and Probation Institute of the Ministry of Defense of the Russian Federation
Russian Federation


I. V. Darmov
Research Centre of Biosecurity of the 33rd Central Research and Probation Institute of the Ministry of Defense of the Russian Federation
Russian Federation


D. V. Pechenkin
Research Centre of Biosecurity of the 33rd Central Research and Probation Institute of the Ministry of Defense of the Russian Federation
Russian Federation


References

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Review

For citations:


Kuklina G.V., Fomenkov O.O., Elagin G.D., Kutaev D.A., Yanov D.S., Kytmanov A.A., Bogacheva N.V., Vorob'eva T.P., Darmov I.V., Pechenkin D.V. Development of the Immuno-Enzyme Test-System for the Detection of Legionella pheumophila, Serogroup I. Problems of Particularly Dangerous Infections. 2011;(4(110)):61-64. (In Russ.) https://doi.org/10.21055/0370-1069-2011-4(110)-61-64

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ISSN 0370-1069 (Print)
ISSN 2658-719X (Online)