Application of Bacillus anthracis Molecular Typing Methods by the Reference Center for the Anthrax Agent Monitoring
https://doi.org/10.21055/0370-1069-2011-4(110)-68-70
Abstract
Presented are the results of B. anthracis molecular typing of in the scope of work of the Reference center for the anthrax agent monitoring. Summarized is the experience of genotyping application in epidemiological investigation of anthrax outbreaks. MLVA-genotyping (8-25 VNTR-loci analysis) of B. anthracis strains, isolated in Russia and in neighboring regions is shown to provide the correct comparison of genotypes with the data of the global MLVA-data bank. The major tasks of reference center for the development of approaches to B. anthracis genotyping are identified. These approaches include research of additional genotyping methods such as SNP analysis, SNR analysis with assessment of the described loci variability and identification of new polymorphic regions.
About the Authors
A. G. Ryazanova
Stavropol Research Anti-Plague Institute
Russian Federation
Russian Federation
E. I. Eremenko
Stavropol Research Anti-Plague Institute
Russian Federation
Russian Federation
O. I. Tsygankova
Stavropol Research Anti-Plague Institute
Russian Federation
Russian Federation
E. A. Tsygankova
Stavropol Research Anti-Plague Institute
Russian Federation
Russian Federation
A. N. Kulichenko
Stavropol Research Anti-Plague Institute
Russian Federation
Russian Federation
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Review
For citations:
Ryazanova A.G., Eremenko E.I., Tsygankova O.I., Tsygankova E.A., Kulichenko A.N. Application of Bacillus anthracis Molecular Typing Methods by the Reference Center for the Anthrax Agent Monitoring. Problems of Particularly Dangerous Infections. 2011;(4(110)):68-70. (In Russ.) https://doi.org/10.21055/0370-1069-2011-4(110)-68-70
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