DFR-Typing of Yersinia pestis Strains from the CIS Natural Foci
https://doi.org/10.21055/0370-1069-2011-2(108)-42-45
Abstract
Different region analysis (DFR-typing) was used for characterization of 275 Y. pestis strains isolated mainly from the CIS natural plague foci. Genomovars (DFR-types) endemic for 27 natural foci were determined. In addition to 32 genomovars described previously 64 novel Y. pestis DFR-types were revealed. 56 genomovars were shown to circulate in CIS and Mongolia. All strains analyzed by DFR-typing, were clustered in accordance with the phylogenetic tree proposed on the basis of combined SNP- and IS100-typing data. The discriminatory ability of the method is high enough to distinguish between subspecies, populations and even strains circulating in certain natural plague focus.
About the Authors
M. E. Platonov
State Research Center for Applied Microbiology and Biotechnology
Russian Federation
Russian Federation
V. V. Evseeva
State Research Center for Applied Microbiology and Biotechnology
Russian Federation
Russian Federation
D. V. Efremenko
Stavropol Research Anti-Plague Institute
Russian Federation
Russian Federation
I. V. Kuznetsova
Stavropol Research Anti-Plague Institute
Russian Federation
Russian Federation
E. V. Chirkova
State Research Center for Applied Microbiology and Biotechnology
Russian Federation
Russian Federation
S. V. Dentovskaya
State Research Center for Applied Microbiology and Biotechnology
Russian Federation
Russian Federation
A. N. Kulichenko
Stavropol Research Anti-Plague Institute
Russian Federation
Russian Federation
A. P. Anisimov
State Research Center for Applied Microbiology and Biotechnology
Russian Federation
Russian Federation
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Review
For citations:
Platonov M.E., Evseeva V.V., Efremenko D.V., Kuznetsova I.V., Chirkova E.V., Dentovskaya S.V., Kulichenko A.N., Anisimov A.P. DFR-Typing of Yersinia pestis Strains from the CIS Natural Foci. Problems of Particularly Dangerous Infections. 2011;(2(108)):42-45. (In Russ.) https://doi.org/10.21055/0370-1069-2011-2(108)-42-45
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