Development of DNA-Biochip for Identification of Influenza A Virus Subtypes
https://doi.org/10.21055/0370-1069-2012-2(112)-89-93
Abstract
Developed was the DNA-biochip to identify subtypes of influenza A virus, pathogenic for humans. Microchip was capable of detecting H1, H3, H5-subtypes of hemagglutinin (including H1-subtype of pandemic A/H1N1(2009) influenza virus ) and neuraminidase subtypes N1,N2 of influenza virus. This microchip was successfully tested on the strains of A/H5N1 highly pathogenic avian influenza virus, A/H1N1(2009) pandemic influenza virus, A/H1N1 and A/H3N2 seasonal influenza viruses.
About the Authors
A. N. Shikov
State Research Centre of Virology and Biotechnology Vector
Russian Federation
Russian Federation
E. I. Sergeeva
State Research Centre of Virology and Biotechnology Vector
Russian Federation
Russian Federation
O. K. Demina
State Research Centre of Virology and Biotechnology Vector
Russian Federation
Russian Federation
V. A. Ternovoy
State Research Centre of Virology and Biotechnology Vector
Russian Federation
Russian Federation
V. V. Ryabinin
Novosibirsk Institute of Chemical Biology and Fundamental Medicine
Russian Federation
Russian Federation
E. V. Kostina
Novosibirsk Institute of Chemical Biology and Fundamental Medicine
Russian Federation
Russian Federation
E. M. Malkova
State Research Centre of Virology and Biotechnology Vector
Russian Federation
Russian Federation
A. N. Sinyakov
Novosibirsk Institute of Chemical Biology and Fundamental Medicine
Russian Federation
Russian Federation
A. P. Agaphonov
State Research Centre of Virology and Biotechnology Vector
Russian Federation
Russian Federation
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Review
For citations:
Shikov A.N., Sergeeva E.I., Demina O.K., Ternovoy V.A., Ryabinin V.V., Kostina E.V., Malkova E.M., Sinyakov A.N., Agaphonov A.P. Development of DNA-Biochip for Identification of Influenza A Virus Subtypes. Problems of Particularly Dangerous Infections. 2012;(2(112)):89-93. (In Russ.) https://doi.org/10.21055/0370-1069-2012-2(112)-89-93
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