Comparative Analysis of inv Gene Structure in Strains of Plague and Pseudotuberculosis Agents
https://doi.org/10.21055/0370-1069-2009-2(100)-50-52
Abstract
Gene inv encoding one of the important pathogenicity factors of pseudotuberculosis agent was analyzed as regards its structure and function in plague microbe of the main and non-main subspecies and pseudotuberculosis microbe. The structure of gene inv was shown to be affected by introduction of insertion sequence IS1541 in all studied Yersinia pestis strains of non-main and main subspecies. This evidences that the loss of functional activity of this gene took place at initial stage of plague agent evolution.
Keywords
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About the Authors
G.N. Odinokov
Russian Anti-Plague Research Institute Microbe
Russian Federation
Russian Federation
G.A. Eroshenko
Russian Anti-Plague Research Institute Microbe
Russian Federation
Russian Federation
V.V. Kutyrev
Russian Anti-Plague Research Institute Microbe
Russian Federation
Russian Federation
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Review
For citations:
Odinokov G., Eroshenko G., Kutyrev V. Comparative Analysis of inv Gene Structure in Strains of Plague and Pseudotuberculosis Agents. Problems of Particularly Dangerous Infections. 2009;(2(100)):50-52. (In Russ.) https://doi.org/10.21055/0370-1069-2009-2(100)-50-52
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