Influence of Serotonin Biogenic Amine on Plague Microbe Growth and Profile of its Proteins in Conditions of Cultivation on Solid Mediums
https://doi.org/10.21055/0370-1069-2008-2(96)-35-39
Abstract
New data on stimulating effect of serotonin biogenic amine on the growth of plague microbe were obtained. A new method for Yersinia pestis isolation from material under consideration, contaminated with concomitant microflora, including environmental objects, by means of bacteriologic method was worked out using serotonin. This method allows reducing the periods of biological accumulation of plague etiological agent down to 24 hours, and increasing the number of colony-forming units (CFU) of plague microbe. Serotonin inhibitory effect to the synthesis of polypeptide with molecular mass of 22 kD was recognized in conditions of cultivating on Hottinger's agar (pH 7.2) at 28 °C during 24 hours.
About the Authors
T. N. Schukovskaya
Russian Anti-Plague Research Institute "Microbe", Saratov
Russian Federation
Russian Federation
S. N. Klueva
Russian Anti-Plague Research Institute "Microbe", Saratov
Russian Federation
Russian Federation
A. L. Kravtsov
Russian Anti-Plague Research Institute "Microbe", Saratov
Russian Federation
Russian Federation
O. A. Volokh
Russian Anti-Plague Research Institute "Microbe", Saratov
Russian Federation
Russian Federation
Yu. A. Aleoshina
Russian Anti-Plague Research Institute "Microbe", Saratov
Russian Federation
Russian Federation
V. V. Kutyrev
Russian Anti-Plague Research Institute "Microbe", Saratov
Russian Federation
Russian Federation
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Review
For citations:
Schukovskaya T.N., Klueva S.N., Kravtsov A.L., Volokh O.A., Aleoshina Yu.A., Kutyrev V.V. Influence of Serotonin Biogenic Amine on Plague Microbe Growth and Profile of its Proteins in Conditions of Cultivation on Solid Mediums. Problems of Particularly Dangerous Infections. 2008;(2(96)):35-39. (In Russ.) https://doi.org/10.21055/0370-1069-2008-2(96)-35-39
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