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The First Case of Yersinia Pestis Subsp. Pestis Isolation in the Territory of Altai Mountain Natural Plague Focus. Communication 1. Microbiological Characteristics, Molecular-Genetic and Mass-Spectrometric Identification of the Isolate

https://doi.org/10.21055/0370-1069-2013-1-60-65

Abstract

Performed is a complex microbiological, molecular-genetic and mass-spectrometric identification of
Yersinia pestis main ssp. strain, which was isolated for the first time in the history of surveillance over the Altai mountain natural plague focus in June, 2012. Determined is its high universal virulence. Plasmid screening, multi-locus VNTR- and mass-spectrometric analyses have revealed the strain to be more closely related to the plague agent variant, circulating in the territory of the natural focus Khuukh-Serkh-Munkh-Khairkhan, Bayan-Ul’giisk aimak, Mongolia.

About the Authors

S. V. Balakhonov
Irkutsk Research Anti-Plague Institute of Siberia and Far East
Russian Federation


M. V. Afanas’Ev
Irkutsk Research Anti-Plague Institute of Siberia and Far East
Russian Federation


M. Yu. Shestopalov
Irkutsk Research Anti-Plague Institute of Siberia and Far East
Russian Federation


A. S. Ostyak
Irkutsk Research Anti-Plague Institute of Siberia and Far East
Russian Federation


S. A. Vityazeva
Irkutsk Research Anti-Plague Institute of Siberia and Far East
Russian Federation


V. M. Korzun
Irkutsk Research Anti-Plague Institute of Siberia and Far East
Russian Federation


D. B. Verzhutsky
Irkutsk Research Anti-Plague Institute of Siberia and Far East
Russian Federation


E. P. Mikhailov
Altai Plague Control Station
Russian Federation


A. I. Mishchenko
Altai Plague Control Station
Russian Federation


A. V. Denisov
Altai Plague Control Station
Russian Federation


N. I. Ivzhenko
Altai Plague Control Station
Russian Federation


E. N. Rozhdestvensky
Altai Plague Control Station
Russian Federation


E. N. Viskov
Altai Plague Control Station
Russian Federation


L. A. Fomina
Altai Plague Control Station
Russian Federation


References

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Review

For citations:


Balakhonov S.V., Afanas’Ev M.V., Shestopalov M.Yu., Ostyak A.S., Vityazeva S.A., Korzun V.M., Verzhutsky D.B., Mikhailov E.P., Mishchenko A.I., Denisov A.V., Ivzhenko N.I., Rozhdestvensky E.N., Viskov E.N., Fomina L.A. The First Case of Yersinia Pestis Subsp. Pestis Isolation in the Territory of Altai Mountain Natural Plague Focus. Communication 1. Microbiological Characteristics, Molecular-Genetic and Mass-Spectrometric Identification of the Isolate. Problems of Particularly Dangerous Infections. 2013;(1):60-65. (In Russ.) https://doi.org/10.21055/0370-1069-2013-1-60-65

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