The First Case of Yersinia Pestis Subsp. Pestis Isolation in the Territory of Altai Mountain Natural Plague Focus. Communication 1. Microbiological Characteristics, Molecular-Genetic and Mass-Spectrometric Identification of the Isolate

Performed is a complex microbiological, molecular-genetic and mass-spectrometric identification of
Yersinia pestis main ssp. strain, which was isolated for the first time in the history of surveillance over the Altai mountain natural plague focus in June, 2012. Determined is its high universal virulence. Plasmid screening, multi-locus VNTR- and mass-spectrometric analyses have revealed the strain to be more closely related to the plague agent variant, circulating in the territory of the natural focus Khuukh-Serkh-Munkh-Khairkhan, Bayan-Ul’giisk aimak, Mongolia.

возбудитель чумы, основной подвид, Алтайский горный природный очаг чумы, Yersinia pestis, вирулентность, плазмидный скрининг, мультилокусный VNTR-анализ, масс-спектрометрический анализ, Altai mountain natural plague focus, plague agent, main subspecies, virulence, plasmid screening, multi-locus VNTR-analysis, mass-spectrometric analysis

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