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Isolation of Central Asian Subspecies of Tularemia Agent in the Altai Territory

https://doi.org/10.21055/0370-1069-2013-1-66-69

Abstract

Within the frames of activities attributed to the Reference Center for tularemia monitoring at SRC AMB, genetically identified are 4 isolates of Francisella tularensis , isolated in 2011 in the Altai Territory. These bacteria prove to be virulent for BALB/c mice, DCL being lower than 10 CFU. Using single-primer PCR-typing and MLVA assay distinguished have been the subspecies of the isolates. Three of them refer to the Central Asian subspecies, one – to the Holarctic, the former being isolated in the territory of the Russian Federation for the first time ever.

About the Authors

A. N. Mokrievich
State Research Center for Applied Microbiology and Biotechnology
Russian Federation


V. S. Timofeev
State Research Center for Applied Microbiology and Biotechnology
Russian Federation


T. Yu. Kudryavtseva
State Research Center for Applied Microbiology and Biotechnology
Russian Federation


G. I. Ulanova
Center of Hygiene and Epidemiology in the Altai Territory
Russian Federation


S. B. Karbysheva
Center of Hygiene and Epidemiology in the Altai Territory
Russian Federation


R. I. Mironova
State Research Center for Applied Microbiology and Biotechnology
Russian Federation


G. M. Vakhrameeva
State Research Center for Applied Microbiology and Biotechnology
Russian Federation


T. I. Gubareva
Center of Hygiene and Epidemiology in the Altai Territory
Russian Federation


V. M. Pavlov
State Research Center for Applied Microbiology and Biotechnology
Russian Federation


I. A. Dyatlov
State Research Center for Applied Microbiology and Biotechnology
Russian Federation


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Review

For citations:


Mokrievich A.N., Timofeev V.S., Kudryavtseva T.Yu., Ulanova G.I., Karbysheva S.B., Mironova R.I., Vakhrameeva G.M., Gubareva T.I., Pavlov V.M., Dyatlov I.A. Isolation of Central Asian Subspecies of Tularemia Agent in the Altai Territory. Problems of Particularly Dangerous Infections. 2013;(1):66-69. https://doi.org/10.21055/0370-1069-2013-1-66-69

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ISSN 0370-1069 (Print)
ISSN 2658-719X (Online)