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Dummy Yersinia pestis Strains: Selection Criteria, Usage Guidelines

https://doi.org/10.21055/0370-1069-2014-3-38-41

Abstract

Objective of the work was to develop selection criteria for the dummy Y. pestis strains, as well as principles of the setting-up a panel and its application for practicing laboratory and differential diagnostics of plague. Studied were the RF regulations, statutory documents and methodological recommendations on the laboratory diagnostics of plague and safety of works with microorganisms; training courses for specialists to qualify for work with the agents of particularly dangerous infections. Research method: analytical. Consequently, established were the term for “dummy strain”; selection criteria for the Y. pestis strains used in the practical course within the frames of the training programme “Microbiology and Laboratory Diagnosis of Plague”; and algorithm of the course application in view of biological risk mitigation during the process of education.

About the Authors

E. V. Sazanova
Russian Research Anti-Plague Institute “Microbe”
Russian Federation


T. A. Malyukova
Russian Research Anti-Plague Institute “Microbe”
Russian Federation


Yu. A. Popov
Russian Research Anti-Plague Institute “Microbe”
Russian Federation


References

1. Vorob’ev A.A., Boev B.V., Bondarenko V.M., Gintsburg A.L. [Bioterrorism issues under current conditions]. Zh. Mikrobiol. Epidemiol. Immunobiol. 2002; 3:3–12.

2. Kutyrev V.V., Popov N.V., Eroshenko G.A., Merkulova T.K. [Plague in Madagascar]. Probl. Osobo Opasn. Infek. 2011; 2(108):5–11.

3. Onishchenko G.G., Kutyrev V.V., editors [Laboratory Diagnostics of Particularly Dangerous Infections. Practice Guidelines]. M.: “Shiko”; 2013. 555 p.

4. Onishchenko G.G., Kutyrev V.V., editors [Natural Plague Foci in the Territory of Caucasus, Caspian Sea Region, Central Asia, and Siberia]. M.: “Meditsina”; 2004. 192 p.

5. [Organization and Carrying out of Epidemiological Surveillance in Natural Plague Foci in the Territory of the Russian Federation. Methodological Regulations]. MR 3.1.3.2355-08. M.; 2009.

6. [Management and carrying out of the laboratory diagnostics of plague in local, regional and national facilities. Methodological Guidelines]. MG 4.2.2940-11. M.; 2011.

7. [Sample preparation containing surrogates of pathological biological agents. Methodological Regulations]. MR 4.2.1103-02. M.; 2002.

8. Sazanova E.V., Boiko A.V., Malyukova T.A., Lotsmanova E.Yu. [Ways of decreasing the probability of emergency situations when training specialists for work with the agents of the I-IV groups of pathogenicity]. Biozashchita i Biobezop. 2012; 1(10):16–20.

9. Trukhachev A.L., Lebedeva S.A., Ivanova V.S. [Modern view on the virulence and level of epidemic hazard among the “Microtus” (rhamnosepositive) plague agent strains]. Epidemiol. Infek. Bol. 2007; 5:4–7.

10. Tsareva N.S., Zaitsev A.A., Bryukhanova G.D., Shchedrin V.I., Sherstyuk M.V. [Yersinia pestis strain used as a test-strain resistant to plague bacteriophage L-413 C]. RF Patent 2203316. 27.04.2003. Bull. 12.

11. Anisimov A.P., Lindler L.E., Pier G.B. Intraspecific Diversity of Yersinia pestis. Clin. Microbiol. Rev. 2004; 17(2):434–64.

12. Devignat R. Varietes de le spece Pasteurella pestis. Nouvelle hypothese. Bull. WHO. 1951; 4(2):242–63.

13. Kutyrev V.V., Smirnova N.I. Genetic Diversity and Genomic Evolution of Particularly Dangerous Infectious Agents of Plague, Cholera and Anthrax: The Present Status and Future Perspective. In: New Research on Biotechnology and Medicine. 2006. P. 29–44.


Review

For citations:


Sazanova E.V., Malyukova T.A., Popov Yu.A. Dummy Yersinia pestis Strains: Selection Criteria, Usage Guidelines. Problems of Particularly Dangerous Infections. 2014;(3):38-41. (In Russ.) https://doi.org/10.21055/0370-1069-2014-3-38-41

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ISSN 0370-1069 (Print)
ISSN 2658-719X (Online)