Application of Dot-Immunoassay for Detection of Plague Agent Antigens in the Field Samples
https://doi.org/10.21055/0370-1069-2014-3-69-71
Abstract
CFU/ml) and soluble antigens (FI) − ≥ 4.8 ng/ml and high specificity, confirmed by the absence of false-positive reactions with five heterologous microorganisms. The test-systems were used for Y. pestis antigen detection in field material from the territory of the Altai mountain natural plague focus by dot-immunoassay with comparison of the received results in passive hemagglutination reaction. Test-systems possessed a number of advantages as compared to routine serological reactions and could be applied with success by practical public health services both in stationary and field conditions.
About the Authors
O. A. Noskova
Irkutsk Research Anti-Plague Institute of Siberia and Far East
Russian Federation
Russian Federation
T. Yu. Zagoskina
Irkutsk Research Anti-Plague Institute of Siberia and Far East
Russian Federation
Russian Federation
E. N. Subycheva
Irkutsk Research Anti-Plague Institute of Siberia and Far East
Russian Federation
Russian Federation
E. Yu. Markov
Irkutsk Research Anti-Plague Institute of Siberia and Far East
Russian Federation
Russian Federation
Yu. O. Popova
Irkutsk Research Anti-Plague Institute of Siberia and Far East
Russian Federation
Russian Federation
L. G. Gridneva
Irkutsk Research Anti-Plague Institute of Siberia and Far East
Russian Federation
Russian Federation
E. P. Mikhailov
Altai Plague Control Station
Russian Federation
Russian Federation
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Review
For citations:
Noskova O.A., Zagoskina T.Yu., Subycheva E.N., Markov E.Yu., Popova Yu.O., Gridneva L.G., Mikhailov E.P. Application of Dot-Immunoassay for Detection of Plague Agent Antigens in the Field Samples. Problems of Particularly Dangerous Infections. 2014;(3):69-71. (In Russ.) https://doi.org/10.21055/0370-1069-2014-3-69-71
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