Mathematical Model of Kinetics of O-Antigen Accumulation in the Process of Periodic Submerged Cultivation of Vibrio cholerae M-41 Ogava with Limitation on Carbon Substrate
https://doi.org/10.21055/0370-1069-2013-1-91-93
Abstract
Developed is the system of differential equations that characterize kinetics of biomass growth, glucose utilization and O-antigen accumulation in the process of submerged cultivation of
V. cholerae strain M-41 Ogawa. The parameters of the mathematic model are identified. Using the developed software in Mathcad 15.0 determined are kinetic constants and coefficients. The mathematical model is demonstrated to describe adequately O-antigen biosynthesis process. The received data can be used in large-scale technology of
V. cholerae strain M-41 submerged cultivation.
V. cholerae strain M-41 Ogawa. The parameters of the mathematic model are identified. Using the developed software in Mathcad 15.0 determined are kinetic constants and coefficients. The mathematical model is demonstrated to describe adequately O-antigen biosynthesis process. The received data can be used in large-scale technology of
V. cholerae strain M-41 submerged cultivation.
About the Authors
A. V. Komissarov
Russian Research Anti-Plague Institute “Microbe”
Russian Federation
Russian Federation
A. K. Nikiforov
Russian Research Anti-Plague Institute “Microbe”
Russian Federation
Russian Federation
S. N. Zadokhin
Russian Research Anti-Plague Institute “Microbe”
Russian Federation
Russian Federation
S. A. Eremin
Russian Research Anti-Plague Institute “Microbe”
Russian Federation
Russian Federation
O. A. Volokh
Russian Research Anti-Plague Institute “Microbe”
Russian Federation
Russian Federation
Yu. A. Aleshina
Russian Research Anti-Plague Institute “Microbe”
Russian Federation
Russian Federation
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Review
For citations:
Komissarov A.V., Nikiforov A.K., Zadokhin S.N., Eremin S.A., Volokh O.A., Aleshina Yu.A. Mathematical Model of Kinetics of O-Antigen Accumulation in the Process of Periodic Submerged Cultivation of Vibrio cholerae M-41 Ogava with Limitation on Carbon Substrate. Problems of Particularly Dangerous Infections. 2013;(1):91-93. (In Russ.) https://doi.org/10.21055/0370-1069-2013-1-91-93
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