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Problems of Particularly Dangerous Infections

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Studies of Ebola Virus persistence in the Body Fluids of a Patient at Advanced Stages of Convalescence

https://doi.org/10.21055/0370-1069-2015-3-73-76

Abstract

At present EVD epidemic, which claimed the lives of more than 10000 people, is still underway in West Africa Countries. Promptness and quality of laboratory diagnostics, alongside with delivered anti-epidemic measures predetermine efficacy of Ebola response operation. Due to a lack of means for the specific prophylaxis and treatment of the disease, asymptomatic patients are discharged from hospitals, based on criteria recommended by WHO, which might be insufficient. Viral RNA is detected in different clinical samples taken from the patients even at the advanced stages of convalescence, which requires essential investigation of peculiarities of Ebola persistence in various biological fluids. The article contains the data on the studies of biological samples, obtained from a female patient diagnosed with Ebola virus disease, applying various methods and techniques.

About the Authors

A. A. Lopatin
Russian Research Anti-Plague Institute “Microbe”
Russian Federation


E. V. Naidenova
Russian Research Anti-Plague Institute “Microbe”
Russian Federation


V. A. Safronov
Russian Research Anti-Plague Institute “Microbe”
Russian Federation


A. S. Razdorsky
Russian Research Anti-Plague Institute “Microbe”
Russian Federation


D. V. Utkin
Russian Research Anti-Plague Institute “Microbe”
Russian Federation


Zh. A. Kas’Yan
Russian Research Anti-Plague Institute “Microbe”
Russian Federation


A. A. Kritsky
Russian Research Anti-Plague Institute “Microbe”
Russian Federation


V. A. Ternovoy
State Research Centre of Virology and Biotechnology “Vector”
Russian Federation


A. E. Nesterov
State Research Centre of Virology and Biotechnology “Vector”
Russian Federation


A. A. Sergeev
State Research Centre of Virology and Biotechnology “Vector”
Russian Federation


A. L. Sylla
Scientific Clinical-Diagnostic Center of Epidemiology and Microbiology
Russian Federation


V. . Kanomou
Scientific Clinical-Diagnostic Center of Epidemiology and Microbiology
Russian Federation


M. Y. Boiro
Pasteur Institute of Guinea
Russian Federation


Yu. V. Demina
Federal Service for Surveillance in the Sphere of Consumers Rights Protection and Human Welfare
Russian Federation


V. Yu. Khoroshilov
Rospotrebnadzor Administration in Saint-Petersburg
Russian Federation


A. Yu. Popova
Federal Service for Surveillance in the Sphere of Consumers Rights Protection and Human Welfare; Russian Medical Academy for Post-Graduate Training
Russian Federation


V. V. Kutyrev
Russian Research Anti-Plague Institute “Microbe”
Russian Federation


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Review

For citations:


Lopatin A.A., Naidenova E.V., Safronov V.A., Razdorsky A.S., Utkin D.V., Kas’Yan Zh.A., Kritsky A.A., Ternovoy V.A., Nesterov A.E., Sergeev A.A., Sylla A.L., Kanomou V., Boiro M.Y., Demina Yu.V., Khoroshilov V.Yu., Popova A.Yu., Kutyrev V.V. Studies of Ebola Virus persistence in the Body Fluids of a Patient at Advanced Stages of Convalescence. Problems of Particularly Dangerous Infections. 2015;(3):73-76. (In Russ.) https://doi.org/10.21055/0370-1069-2015-3-73-76

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ISSN 0370-1069 (Print)
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