Non-Specific Prophylaxis of Plague in the Gorno-Altai High-Mountain Natural Focus in 2016

Objective of the study is to substantiate performance, assess the conditions, and analyze the results of activities on non-specific plague prophylaxis in the epizootic territory. Materials and methods. Utilized were archival data and operational reports of Altai Plague Control Station, Irkutsk RAPI, RusRAPI “Microbe”, Center of Hygiene and Epidemiology in the Republic of Altai, and Rospotrebnadzor Administration in the Republic of Altai, as well as literature sources. Spatial analysis was carried out using GIS-technologies. Results and conclusions. Concerted and coordinated activities of the Rospotrebnadzor institutions, medical and veterinary institutions, local executive authorities have allowed for complex prophylactic and anti-epidemic measures on prevention of plague dissemination and transmission in the territory of the Republic of Altai in 2016. Demonstrated has been the necessity to expand the scope and scale of operations and scientific research in the focus, deploying advanced toolkit of methods and means. 

1. Ad’yasuren Z., Tserennorov D., Otgonbaatar D., Balakhonov S.V., Innokent`eva T.I., Agiymaa Sh., Kosilko S.A. [Clinical-epidemiological fea- tures of plague in Mongolia]. Probl. Osobo Opasn. Infek. 2010; 1(103):30–3.

2. Balakhonov S.V., Korzun V.M., Verzhutsky D.B., Mikhaylov E.P., Rozhdestvensky E.N., Denisov A.V. [The first case of Yersinia pestis subsp. pestis isolation in the territory of the Altai mountain natural plague focus. Communication 2. Probable ways and mechanisms of plague agent main sub- species importation into the territory of the focus]. Probl. Osobo Opasn. Infek. 2013; 2:5–10.

3. Balakhonov S.V., Korzun V.M., Kosilko S.A., Mikhailov E.P., Shchuchinov L.V., Mishchenko A.I., Zarubin I.V., Rozhdestvensky E.N., Denisov A.V. [Actual aspects of epidemiological well-being support as re- gards plague for population in Altai Republic]. Epidemiol. Vaktsinoprofilakt. 2016; 4(89):42–7.

4. Balakhonov S.V., Korzun V.M., editors. [Gorno-Altai Natural Plague Focus: Retrospective Analysis, Epizootiological Monitoring, and Current State]. Novosibirsk: “Nauka-Tsentr”; 2014. 272 p.

5. Balakhonov S.V., Popova A.Yu., Mishchenko A.I., Mikhailov E.P., Ezhlova E.B., Demina Yu.V., Denisov A.V., Rozhdestvensky E.N., Bazarova G.Kh., Shchuchinov L.V., Zarubin I.V., Semenova Zh.E., Madenova N.M., Dyusenbaev D.K., Yarygina M.B., Chipanin E.V., Kosilko S.A., Noskov A.K., Korzun V.M. [A case of human infection with plague in the Kosh-Agach Region of the Republic of Altai in 2015. Communication 1. Clinicalepidemiological and epizootiological aspects]. Probl. Osobo Opasn. Infek. 2016; 1:55–60.

6. Golubinsky E.P., Zhovty I.F., Lemesheva L.B. [Concerning Plague in Siberia]. Irkutsk: Publishing House of Irkutsk University; 1987. 243 p.

7. Kutyrev V.V., Popova A.Yu., Ezhlova E.B., Demina Yu.V., Pakskina N.D., Shchuchinov L.V., Mikhailov E.P., Mishchenko A.I., Rozhdestvensky E.N., Bazarova G.Kh., Denisov A.V., Sharova I.N., Popov N.V., Kuznetsov A.A. [Infection of an individual with plague in the Gorno-Altaisk high-mountain natural focus in 2014. Communication 1. Epidemiological and epizootiological peculiarities of plague manifestations in the Gorno-Altaisk high-mountain (Sailyugemsky) natural plague focus]. Probl. Osobo Opasn. Infek. 2014; 4:9–16.

8. Kucheruk V.V., Bibikov D.I. [Marmots as plague reservoirs]. In: [Marmots. Biocoenotic and Practical Significance]. M.: “Nauka”; 1980. P. 111–164.

9. Lobanov V.N. [Plague in Camels and its Significance in Epidemiology]. Saratov: Publishing House of the Saratov University; 1968. 128 p.

10. Matrosov A.N. [Modern conception of non-specific disease pro- phylaxis in complex natural foci of plague and other infections in the territory of Russia]. Dez. Delo. 2014; 1:30–2.

11. Matrosov A.N., Kuznetsov A.A., Knyazeva T.V., Verzhutsky D.B., Nikitin A.Ya., Nemchenko L.S., Grigor’ev M.P., Levchenko B.I., Bobenko O.A., Gazieva A.Yu., Korotkov V.B. [Modern conception of the control over the abundance of carriers and vectors of plague in the territory of the Russian Federation]. Probl. Osobo Opasn. Infek. 2012; 2(112):16–20.

12. Naurusbaev E.O., Kul’dzhataev D.M., Tipikin A.S., Shashkov V.D., Tudakhunov B.B. [Distribution and the Numbers of the Grey marmot in the central part of Karkara river basin]. Karantin. Zoonoz. Infek. v Kazakhstane. Almaty, 2014; 1(29):68–70.

13. Nikitin A.Ya., Maramovich A.S., Kossilko S.A., Innokentieva T.I., Bazanova L.P., Balakhonov S.V., Voronova G.A., Okunev L.P. [Epizootiologic characterization of plague natural foci in Mongolia in connection with desig- nation of protection measures from import and dissemination of the infection into the Russian Territory]. Probl. Osobo Opasn. Infek. 2007; 2(94):28–32.

14. Onishchenko G.G., Kutyrev V.V., editors. [Natural Plague Foci in the Territory of Caucasus, Caspian Sea Region, Central Asia, and Siberia]. M.: “Meditsina”; 2004. 192 p.

15. Popkov A.F., Verzhutsky D.B., Korzun V.M., Innokentieva T.I., Chipanin E.V., Vershinin E.A., Nemchenko L.S., Nikitin A.Ya., Okunev L.P., Bazanova L.P., Tokmakova E.G., Voronova G.A., Logacheov V.I., Mikhailov E.P., Feodorov S.V., Agapov V.A. [Summing-up the results of the population- al and ecological investigations into plague natural focality in Siberia, carried out in 2001–2005]. Probl. Osobo Opasn. Infek. 2007; 2(94):33–6.

16. Popov N.V., Bezsmertny V.E., Matrosov A.N., Knyazeva T.V., Kuznetsov A.A., Fedorov Yu.M., Popov V.P., Verzhutsky D.B., Korzun V.M., Kosilko S.A., Chipanin E.V., Dubyansky V.M., Maletskaya O.V., Grigor’ev M.P., Zenkevich E.S., Toporkov V.P., Balakhonov S.V., Kulichenko A.N., Kutyrev V.V. [Epizootic activity of natural plague foci of the Russian Federation in 2015, and prognosis for 2016]. Probl. Osobo Opasn. Infek. 2016; 1:13–9.

17. Skorodumov A.M. [Plague in Siberia]. Irkutsk; 1937. 234 p.

18. Sludsky A.A. [Plague Epizootiology (Review of Studies and Hipotheses)]. Deposit to All-Russian Institute of Scientific and Technical in- formation No 231-B2014. 2014. 313 p. [cited 15 Oct 2016]. Available from: http://www.microbe.ru/deponir/.