Development of the Experimental Technology for Protective Antigens of Vibrio cholerae 569B Inaba Concentration by Means of Tangential Ultrafiltration
https://doi.org/10.21055/0370-1069-2011-3(109)-75-77
Abstract
Worked out is the experimental technology for protective antigens of Vibrio cholerae 569 B Inaba (cholera-anatoxin and O-antigen) concentrating by means of tangential ultrafiltration. Optimization of concentrating technological process is carried out. This technique makes it possible to obtain cholera vaccine components meeting all regulatory requirements.
Keywords
616.932:576.809.7
About the Authors
A. V. Komissarov
Russian Research Anti-Plague Institute Microbe
Russian Federation
Russian Federation
S. A. Eremin
Russian Research Anti-Plague Institute Microbe
Russian Federation
Russian Federation
A. Yu. Ul`yanov
Russian Research Anti-Plague Institute Microbe
Russian Federation
Russian Federation
Yu. A. Aleshina
Russian Research Anti-Plague Institute Microbe
Russian Federation
Russian Federation
A. K. Nikiforov
Russian Research Anti-Plague Institute Microbe
Russian Federation
Russian Federation
Yu. G. Vasin
Russian Research Anti-Plague Institute Microbe
Russian Federation
Russian Federation
O. D. Klokova
Russian Research Anti-Plague Institute Microbe
Russian Federation
Russian Federation
N. I. Belyakova
Russian Research Anti-Plague Institute Microbe
Russian Federation
Russian Federation
References
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3. Komissarov A.V., Komosko G.V., Leshchenko A.A. et al. [Study of sterilization filtration process of the liquid anti-anthrax equine globulin]. Biotechnology. 2002; 2:66–74.
4. Cherkasov A.N., Pasechnik V.A. [Membranes and sorbents in bio- technology]. Leningrad: Khimiya; 1991. 239 p.
Review
For citations:
Komissarov A.V., Eremin S.A., Ul`yanov A.Yu., Aleshina Yu.A., Nikiforov A.K., Vasin Yu.G., Klokova O.D., Belyakova N.I. Development of the Experimental Technology for Protective Antigens of Vibrio cholerae 569B Inaba Concentration by Means of Tangential Ultrafiltration. Problems of Particularly Dangerous Infections. 2011;(3(109)):75-77. (In Russ.) https://doi.org/10.21055/0370-1069-2011-3(109)-75-77
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