Nucleotide Sequence and Phylogenetic Analysis of Glycoprotein-G of the Russian Fixed Rabies Virus Strain “Moscow 3253”
https://doi.org/10.21055/0370-1069-2013-4-73-75
Abstract
Fully sequenced have been glycoprotein-G, sha-psi region, as well as H-end site of the L-gene in the rabies virus strain “Moscow 3253”. Compared are amino acid sequences of proteins of “Moscow 3253” strain and other fixed strains of the virus. Established is 98 % DNA homology with RV-97, and 91% homology with PV (Pasteur virus) strain. Constructed has been phylogenetic tree of the strain under study alongside with various groups of fixed rabies virus. It is revealed that “Moscow 3253” strain has closer genetic relations with Japanese group of strains, than with PV strain. Put forward is an assumption that PV strain does not derive from the virus isolated by Pasteur, but relates to the American group of strains.
About the Authors
I. V. Tuchkov
Russian Research Anti-Plague Institute “Microbe”
Russian Federation
Russian Federation
Ya. M. Krasnov
Russian Research Anti-Plague Institute “Microbe”
Russian Federation
Russian Federation
A. A. Goryaev
Russian Research Anti-Plague Institute “Microbe”
Russian Federation
Russian Federation
Zh. V. Matveeva
Russian Research Anti-Plague Institute “Microbe”
Russian Federation
Russian Federation
A. V. Stepanov
Russian Research Anti-Plague Institute “Microbe”
Russian Federation
Russian Federation
N. V. Mayorov
Russian Research Anti-Plague Institute “Microbe”
Russian Federation
Russian Federation
A. K. Nikiforov
Russian Research Anti-Plague Institute “Microbe”
Russian Federation
Russian Federation
References
1. Gamaleya N.F., Mechnikov I.I., Timiryazev K.A. [Pasteur]. USSR Science Academy publishing house; 1946. 52 p.
2. Gruzdev K.N., Nedosekov V.V. [Rabies in Animals]. M.: Akvarium; 2001. 301 p.
3. Selimov M.A. [Rabies]. M.: Meditsina; 1978. 334 p.
4. Sacramento D., Badrane H., Bourhy H., Tordo N. Molecular epidemiology of rabies virus in France: comparison with vaccine strains. J. Gen. Virol. 1992; 73:1149–58.
5. Fauquet C.M., Mayo M.A., Maniloff J., Desselberger U., Ball L.A. Virus Taxonomy. Classification and Nomenclature of Viruses: The Eighth Report of the International Committee on Taxonomy of Viruses. Part II – The Negative Sense Single Stranded RNA Viruses. Elsevier Academic Press; 2005. P. 609–14.
6. Faber M., Faber M.L., Papaneri A., Bette M., Weihe E., Dietzschold B., Schnell M.J. A single amino acid change in rabies virus glycoprotein increases virus spread and enhances virus pathogenicity. J. Virol. 2005; 79:14141–8.
7. Metlin A., Paulin L., Suomalainen S., Neuvonen E., Rybakov S., Mikhalishin V., Huovilainen A. Characterization of Russian rabies virus vaccine strain RV-97. Virus Res. 2008; 132(1–2):242–7.
8. Sakamoto S., Nakatake H., Tokiyoshi S., Yamamoto M., Kawai A., Smith. Studies on the antigenicity and nucleotide sequence of the rabies virus Nishigahara strain, a current seed strain used for dog vaccine production in Japan. Virus Genes. 1994; 8(1):35–46
9. Wenqiang Jiao, Xiangping Yin, Zhiyong Li, Xi Lan, Xuerui Li, Xiaoting Tian, Baoyu Li, Bin Yang, Yun Zhang, Jixing Liu. Molecular characterization of China virus vaccine strain. Virol. J. 2011; 8:521
Review
For citations:
Tuchkov I.V., Krasnov Ya.M., Goryaev A.A., Matveeva Zh.V., Stepanov A.V., Mayorov N.V., Nikiforov A.K. Nucleotide Sequence and Phylogenetic Analysis of Glycoprotein-G of the Russian Fixed Rabies Virus Strain “Moscow 3253”. Problems of Particularly Dangerous Infections. 2013;(4):73-75. (In Russ.) https://doi.org/10.21055/0370-1069-2013-4-73-75
Views:
848
Email this article 