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Analysis of the SXT Constin of Antibiotic-Sensitive Vibrio cholerae Strain of Non-O1/ Non-O139 Serogroup

https://doi.org/10.21055/0370-1069-2012-3-102-103

Abstract

In the genome of antibiotic-sensitive
Vibrio cholerae strain belonging to O50 serogroup, isolated in the territory of the Russian Federation in 1974, detected is the SXT conjugative trasposone – SXT constin. Analysis if its structure revealed that it does not contain genes of resistance to such antibiotics as streptomycin, sulfamethoxasole, trimethoprim, chloramphenicol, and kanamycin, being, probably, one of the predecessors of antibiotic-resistant SXT constins which spread out within the genomes of epidemic
Vibrio cholerae O139 strains in 1992.

About the Authors

A. V. Fadeeva
Russian Research Anti-Plague Institute “Microbe”
Russian Federation


G. A. Eroshenko
Russian Research Anti-Plague Institute “Microbe”
Russian Federation


N. Yu. Shavina
Russian Research Anti-Plague Institute “Microbe”
Russian Federation


V. V. Kutyrev
Russian Research Anti-Plague Institute “Microbe”
Russian Federation


References

1. Eroshenko G.A., Odinokov G.N., Anisimova L.V., Shavina N.Yu., Vinogradova N.A., Kutyrev V.V. [Antibiotic-resistant strains of plague agent and development of procedure for their detection by PCR method]. Probl. Osobo. Opasn. Infek. 2011; (107):53–7.

2. Hochhut B., Lotfi Y., Mazel D., Faruque S.M., Woodgate R., Waldor M.K. Molecular analysis of antibiotic resistance gene clusters in Vibrio cholerae O139 and O1 constins. Antimicrob. Agents Chemother. 2001; 45:2991–3000.


Review

For citations:


Fadeeva A.V., Eroshenko G.A., Shavina N.Yu., Kutyrev V.V. Analysis of the SXT Constin of Antibiotic-Sensitive Vibrio cholerae Strain of Non-O1/ Non-O139 Serogroup. Problems of Particularly Dangerous Infections. 2012;(3(113)):102-103. (In Russ.) https://doi.org/10.21055/0370-1069-2012-3-102-103

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ISSN 0370-1069 (Print)
ISSN 2658-719X (Online)