Detection of Clones with Different Expression of Virulence and Persistence Factors in Natural Populations of Cholera Vibrio and Their Phenotypic Analysis
https://doi.org/10.21055/0370-1069-2009-3(101)-39-43
Abstract
Analysis of the population structure of 41 Vibrio cholerae biovar eltor natural strains permitted to detect 12 strains forming typical transparent and atypical opaque colonies. Among the later were identified 3 strains which morphology variability correlated with altered production of exopolysaccharide, cholera toxin, hemolysine, soluble hemagglutinin/protease and altered mobility. One of the external signals causing coordinating switching of production of the indicated pathogenicity and persistence factors is alkaline (pH 9,0) reaction of the medium.
Keywords
Vibrio cholerae,
heterogeneous population,
coordinated change of virulence and persistence gene expression
616.932:576.8.097.21
About the Authors
S. P. Zadnova
Russian Research Anti-Plague Institute Microbe
Russian Federation
Russian Federation
L. F. Livanova
Russian Research Anti-Plague Institute Microbe
Russian Federation
Russian Federation
Yu. V. Lozovskiy
Russian Research Anti-Plague Institute Microbe
Russian Federation
Russian Federation
N. I. Smirnova
Russian Research Anti-Plague Institute Microbe
Russian Federation
Russian Federation
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Review
For citations:
Zadnova S.P., Livanova L.F., Lozovskiy Yu.V., Smirnova N.I. Detection of Clones with Different Expression of Virulence and Persistence Factors in Natural Populations of Cholera Vibrio and Their Phenotypic Analysis. Problems of Particularly Dangerous Infections. 2009;(3(101)):39-43. (In Russ.) https://doi.org/10.21055/0370-1069-2009-3(101)-39-43
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