Сидерофоры Bacillus anthracis
https://doi.org/10.21055/0370-1069-2016-1-68-74
Аннотация
Железо необходимо для роста и размножения бактерий. Один из способов приобретения железа Bacillus anthracis состоит в использовании высокоаффинных хелатирующих агентов ионов железа - сидерофоров бациллибактина и петробактина, извлекающих железо из трансферрина и ферритина клеток хозяина. Функции бациллибактина и петробактина реализуются на разных стадиях роста B. anthracis in vivo , при этом синтез петробактина необходим также и для проявления вирулентности микроба. Знание путей биосинтеза сидерофоров способствует разработке блокирующих эти пути новых терапевтических средств против сибирской язвы. В обзоре приведены сведения о структуре, генетике, функциях сидерофоров сибиреязвенного микроба.
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Рецензия
Для цитирования:
Еременко Е.И. Сидерофоры Bacillus anthracis. Проблемы особо опасных инфекций. 2016;(1):68-74. https://doi.org/10.21055/0370-1069-2016-1-68-74
For citation:
Eremenko E.I. Bacillus anthracis Siderophores . Problems of Particularly Dangerous Infections. 2016;(1):68-74. (In Russ.) https://doi.org/10.21055/0370-1069-2016-1-68-74
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