IMMUNOMODULATORS AND SPECIFIC PROPHYLAXIS OF INFECTIOUS DISEASES
https://doi.org/10.21055/0370-1069-2017-3-21-26
Abstract
The high-priority task of prospective preventive vaccination consists in the development of differentiated approaches to vaccination with the aim of generation of effective immunity in each immunized person, using various dosages and vaccination regimes as well as adjuvants and accessory means of immune response modulation. At present, multiple investigations are dedicated to the search of immunoadjuvants capable of inducing immune response even in individuals with compromised immune activity and immunodeficiency signs. The review exemplifies combined usage of different groups of immunobiological agents in domestic applied medicine – vaccines, immunomodulators, cytokines, as well as prospective preparations, prequalified and recommended for clinical trials. The review covers major objectives, additional approaches and focus areas in experimental immunology related to the advancement of vaccinal prevention of infectious diseases of different etiology applying preparations capable of stimulating the induction of postvaccinal immunity. Proper attention is given to the possibility of immunomodulator usage in the specific prophylaxis of particularly dangerous infections.
About the Authors
N. D. Omel’chenko
Rostov-on-Don Research Anti-Plague Institute
Russian Federation
Rostov-on-Don
Russian Federation
Rostov-on-Don
I. A. Ivanova
Rostov-on-Don Research Anti-Plague Institute
Russian Federation
Rostov-on-Don
Russian Federation
Rostov-on-Don
I. A. Bespalova
Rostov-on-Don Research Anti-Plague Institute
Russian Federation
Rostov-on-Don
Russian Federation
Rostov-on-Don
A. V. Filippenko
Rostov-on-Don Research Anti-Plague Institute
Russian Federation
Rostov-on-Don
Russian Federation
Rostov-on-Don
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Review
For citations:
Omel’chenko N.D., Ivanova I.A., Bespalova I.A., Filippenko A.V. IMMUNOMODULATORS AND SPECIFIC PROPHYLAXIS OF INFECTIOUS DISEASES. Problems of Particularly Dangerous Infections. 2017;(3):21-26. (In Russ.) https://doi.org/10.21055/0370-1069-2017-3-21-26
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